Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 11131
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563034(US11407736, Compound II-28 | US11578078, Compound ...)
Affinity DataIC50: 16.1nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593700((S)-4-benzyl-N-(5-methyl-4-oxo-7-(7-oxa-2-azaspiro...)
Affinity DataIC50: 23.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563033(US11407736, Compound II-27 | US11578078, Compound ...)
Affinity DataIC50: 27.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593684((S)-N-(8-(6-(3-hydroxy-3-methylbut-1-yn-1-yl)pyrid...)
Affinity DataIC50: 33.4nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563035(US11407736, Compound II-31 | US11578078, Compound ...)
Affinity DataIC50: 36.3nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593690((S)-5-benzyl-N-(1-methyl-2-oxo-8-(7-oxa-2-azaspiro...)
Affinity DataIC50: 36.6nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593696((S)-1-benzyl-N-(1-methyl-2-oxo-8-(7-oxa-2-azaspiro...)
Affinity DataIC50: 38.8nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593693(US11578078, Compound I-19 | US11578078, Compound I...)
Affinity DataIC50: 41.3nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593692(N-(1-methyl-2-oxo-8-(3-oxa-9-azaspiro[5.5]undecan-...)
Affinity DataIC50: 46.4nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593701((S)-4-(4-fluorobenzyl)-N-(5-methyl-7-(9-methyl-3,9...)
Affinity DataIC50: 48.8nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593693(US11578078, Compound I-19 | US11578078, Compound I...)
Affinity DataIC50: 54nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563018(US11407736, Compound I-236 | US11578078, Compound ...)
Affinity DataIC50: 55.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM590926(US11564930, Compound I-16)
Affinity DataIC50: 60.4nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593691(US11578078, Compound I-17 | US11578078, Compound I...)
Affinity DataIC50: 61.2nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593691(US11578078, Compound I-17 | US11578078, Compound I...)
Affinity DataIC50: 61.2nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM563017(US11407736, Compound I-235 | US11578078, Compound ...)
Affinity DataIC50: 62.1nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM590927(US11564930, Compound I-17)
Affinity DataIC50: 70.4nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593689(5-benzyl-N-(1-(methyl-d3)-2-oxo-8-(7-oxa-2-azaspir...)
Affinity DataIC50: 106nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593678((S)-N-(5-methyl-4-oxo-8-(3-oxa-9-azaspiro[5.5]unde...)
Affinity DataIC50: 193nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593688(5-benzyl-N-(1-methyl-2-oxo-8-(3-oxa-9-azaspiro[5.5...)
Affinity DataIC50: 373nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593685(5-benzyl-N-(2-oxo-8-(7-oxa-2-azaspiro[3.5]nonan-2-...)
Affinity DataIC50: 414nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593687(5-benzyl-N-(1-methyl-2-oxo-8-(2-azaspiro[3.5]nonan...)
Affinity DataIC50: 444nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593694(N-(1-methyl-2-oxo-8-(2-azaspiro[3.5]nonan-2-yl)-2,...)
Affinity DataIC50: 603nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593686(N-(8-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-1-methyl-...)
Affinity DataIC50: 808nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent