Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 11037
TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587509(US11535596, Compound CNS23-D2)
Affinity DataIC50: 11.1nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587505(US11535596, Compound CNS6-A1-D2)
Affinity DataIC50: 21.8nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587511(US11535596, Compound CNS25)
Affinity DataIC50: 28.4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataIC50: 29.1nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587517(US11535596, Compound CNS-222)
Affinity DataIC50: 50nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataIC50: 57.8nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587513(US11535596, Compound CNS26)
Affinity DataIC50: 79.1nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataIC50: 137nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587504(US11535596, Compound CNS6)
Affinity DataIC50: 172nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587506(US11535596, Compound CNS6-A2)
Affinity DataIC50: 247nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM50001000(CHEBI:29133 | DEXTRORPHAN | US11535596, Compound D...)
Affinity DataIC50: 259nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 527nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM50001000(CHEBI:29133 | DEXTRORPHAN | US11535596, Compound D...)
Affinity DataIC50: 1.53E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataIC50: 5.25E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataIC50: 6.82E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587506(US11535596, Compound CNS6-A2)
Affinity DataIC50: 7.08E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587513(US11535596, Compound CNS26)
Affinity DataIC50: 8.85E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587507(US11535596, Compound CNS7-M)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587511(US11535596, Compound CNS25)
Affinity DataIC50: 1.46E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587505(US11535596, Compound CNS6-A1-D2)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587509(US11535596, Compound CNS23-D2)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587504(US11535596, Compound CNS6)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587520(US11535596, Compound CNS27-D2)
Affinity DataKi:  1.60nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587509(US11535596, Compound CNS23-D2)
Affinity DataKi:  7.80nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587505(US11535596, Compound CNS6-A1-D2)
Affinity DataKi:  15.3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587511(US11535596, Compound CNS25)
Affinity DataKi:  20nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataKi:  20.5nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587516(US11535596, Compound CNS1-D5)
Affinity DataKi:  22nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataKi:  40.6nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587513(US11535596, Compound CNS26)
Affinity DataKi:  55.6nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587521(US11535596, Compound N-desmethyl CNS1-D2)
Affinity DataKi:  70nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi:  96.3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587504(US11535596, Compound CNS6)
Affinity DataKi:  121nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM50001000(CHEBI:29133 | DEXTRORPHAN | US11535596, Compound D...)
Affinity DataKi:  182nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataKi:  371nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM50001000(CHEBI:29133 | DEXTRORPHAN | US11535596, Compound D...)
Affinity DataKi:  1.11E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587521(US11535596, Compound N-desmethyl CNS1-D2)
Affinity DataKi:  3.08E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataKi:  3.81E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM213826(Dextromethorphan | US11535596, Compound Dextrometh...)
Affinity DataKi:  4.52E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587516(US11535596, Compound CNS1-D5)
Affinity DataKi:  9.90E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587511(US11535596, Compound CNS25)
Affinity DataKi:  1.06E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587520(US11535596, Compound CNS27-D2)
Affinity DataKi: >2.30E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In DepthDetails
US Patent