Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 11000
TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM488640(US10961228, Example Tofacitinib | US11414413, Exam...)
Affinity DataIC50: 0.720nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584206(US11524961, Compound LW104-A | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584206(US11524961, Compound LW104-A | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584217(US11524961, Compound LW104-M | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584216(US11524961, Compound LW104-L | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584216(US11524961, Compound LW104-L | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584218(US11524961, Compound LW104-N | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584218(US11524961, Compound LW104-N | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584217(US11524961, Compound LW104-M | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584209(US11524961, Compound LW104-D | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584219(US11524961, Compound LW104-O | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584210(US11524961, Compound LW104-E | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584210(US11524961, Compound LW104-E | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM488640(US10961228, Example Tofacitinib | US11414413, Exam...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584209(US11524961, Compound LW104-D | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584220(US11524961, Compound LW104-P | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584211(US11524961, Compound LW104-F | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM488640(US10961228, Example Tofacitinib | US11414413, Exam...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584211(US11524961, Compound LW104-F | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 5nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584213(US11524961, Compound LW104-I | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584212(US11524961, Compound LW104-G | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584212(US11524961, Compound LW104-G | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584219(US11524961, Compound LW104-O | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584208(US11524961, Compound LW104-C | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584213(US11524961, Compound LW104-I | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584208(US11524961, Compound LW104-C | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584220(US11524961, Compound LW104-P | US11524961, Compoun...)
Affinity DataIC50: 55nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 69.3nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584206(US11524961, Compound LW104-A | US11524961, Compoun...)
Affinity DataIC50: 98.3nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 116nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584207(US11524961, Compound LW104-K | US11524961, Compoun...)
Affinity DataIC50: 136nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584211(US11524961, Compound LW104-F | US11524961, Compoun...)
Affinity DataIC50: 145nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584216(US11524961, Compound LW104-L | US11524961, Compoun...)
Affinity DataIC50: 158nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584212(US11524961, Compound LW104-G | US11524961, Compoun...)
Affinity DataIC50: 158nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584210(US11524961, Compound LW104-E | US11524961, Compoun...)
Affinity DataIC50: 187nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584209(US11524961, Compound LW104-D | US11524961, Compoun...)
Affinity DataIC50: 190nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584217(US11524961, Compound LW104-M | US11524961, Compoun...)
Affinity DataIC50: 194nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584218(US11524961, Compound LW104-N | US11524961, Compoun...)
Affinity DataIC50: 203nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584220(US11524961, Compound LW104-P | US11524961, Compoun...)
Affinity DataIC50: 216nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584219(US11524961, Compound LW104-O | US11524961, Compoun...)
Affinity DataIC50: 294nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584208(US11524961, Compound LW104-C | US11524961, Compoun...)
Affinity DataIC50: 427nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Shanghai Longwood Biopharmaceuticals

US Patent
LigandPNGBDBM584213(US11524961, Compound LW104-I | US11524961, Compoun...)
Affinity DataIC50: 649nMAssay Description:Kinase Assay:Preparation of buffers, the buffer included 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2, and 1 mM EGTA.After the buffer was formula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent