Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 10993
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582491(US11518779, Compound 7)
Affinity DataIC50: 700nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
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TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582494(US11518779, Compound 33)
Affinity DataIC50: 800nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582492(US11518779, Compound 10)
Affinity DataIC50: 1.10E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582496(US11518779, Compound 56)
Affinity DataIC50: 1.90E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582497(US11518779, Compound 70)
Affinity DataIC50: 2.20E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582493(US11518779, Compound 21)
Affinity DataIC50: 3.60E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582498(US11518779, Compound 86)
Affinity DataIC50: 6.00E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582495(US11518779, Compound 42)
Affinity DataIC50: 1.54E+4nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent