Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 10871
TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575844(US11466005, Compound 16 | 6-(1,4-Dimethyl-1H-1,2,3...)
Affinity DataIC50: 0.300nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575868(US11466005, Compound 34 | 4-((6-(1,4-dimethyl-1H-1...)
Affinity DataIC50: 0.340nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575845(US11466005, Compound 2 | (S)-2-(6-(3,5-dimethyliso...)
Affinity DataIC50: 0.350nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575867(US11466005, Compound 13 | (S)-2-(6-(1,4-Dimethyl-1...)
Affinity DataIC50: 0.400nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575781(US11466005, Compound 1 | (S)-2-(6-(3,5-dimethyliso...)
Affinity DataIC50: 0.480nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575853(US11466005, Compound 6 | (S)-2-(6-(1,4-dimethyl-1H...)
Affinity DataIC50: 0.490nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575852(US11466005, Compound 23 | 2-(4-((3-Fluoropyridin-2...)
Affinity DataIC50: 0.540nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575846(US11466005, Compound 17 | 6-(1,4-dimethyl-1H-1,2,3...)
Affinity DataIC50: 0.550nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575849(US11466005, Compound 4 | 2-(6-(1,4-Dimethyl-1H-1,2...)
Affinity DataIC50: 0.570nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575851(US11466005, Compound 5 | 2-(6-(1,4-Dimethyl-1H-1,2...)
Affinity DataIC50: 0.590nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575869(US11466005, Compound 15 | 6-(1,4-Dimethyl-1H-1,2,3...)
Affinity DataIC50: 0.610nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575847(US11466005, Compound 3 | 2-(6-(1,4-Dimethyl-1H-1,2...)
Affinity DataIC50: 0.660nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575856(US11466005, Compound 26 | 2-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 0.680nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575850(US11466005, Compound 19 | 3-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 0.790nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575854(US11466005, Compound 24 | 2-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 0.880nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575855(US11466005, Compound 7 | (S)-2-(6-(1,4-dimethyl-1H...)
Affinity DataIC50: 0.970nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575859(US11466005, Compound 9 | 2-(6-(3,5-dimethylisoxazo...)
Affinity DataIC50: 0.990nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575848(US11466005, Compound 18 | 2-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 1.10nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575863(US11466005, Compound 11 | 2-(6-(1,4-dimethyl-1H-1,...)
Affinity DataIC50: 1.30nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575865(US11466005, Compound 12 | 2-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 1.60nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575860(US11466005, Compound 29 | (S)—N-(6-(1,4-dimet...)
Affinity DataIC50: 1.90nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575861(US11466005, Compound 10 | 2-(6-(1,4-dimethyl-1H-1,...)
Affinity DataIC50: 2.20nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575862(US11466005, Compound 30 | (R)-2-(6-(1,4-dimethyl-1...)
Affinity DataIC50: 3nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575864(US11466005, Compound 31 | (R)-2-(6-(3,5-dimethylis...)
Affinity DataIC50: 4.60nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575866(US11466005, Compound 33 | 6-(1,4-dimethyl-1H-1,2,3...)
Affinity DataIC50: 4.67nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575857(US11466005, Compound 8 | 2-(6-(3,5-dimethylisoxazo...)
Affinity DataIC50: 12nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575858(US11466005, Compound 27 | 2-(6-(1,4-Dimethyl-1H-1,...)
Affinity DataIC50: 17nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by Echo 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent