Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 10823
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571544(US11446301, Compound 1)
Affinity DataIC50: 0.0430nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571545(US11446301, Compound 2)
Affinity DataIC50: 0.0860nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571548(US11446301, Compound 5)
Affinity DataIC50: 0.140nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571546(US11446301, Compound 3)
Affinity DataIC50: 0.240nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571547(US11446301, Compound 4)
Affinity DataIC50: 0.270nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571550(US11446301, Compound 8)
Affinity DataIC50: 0.970nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Nanjing Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM571549(US11446301, Compound 7)
Affinity DataIC50: 2.10nMAssay Description:The TR-FRET assay can monitor formation of the product 3,4,5-inositol triphosphate molecule (PIP3) as it competed with fluorescently labeled PIP3 for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
Go to US Patent