Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 10767
TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438807((S)-4-(2-(2-((2'-chloro-3'-(5- (2-hydroxypropyl)-1...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438816(4,4′-(((((2-chloro-2′-cyano-[1,1′...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438815(4-(2-(2-((2-chloro-2'-cyano- 3'-(5-(2-hydroxyethyl...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438814((R)-4-(2-(2-((2-chloro-2′-cyano-3′-(5-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438813(4-(2-(2-((2-chloro-2'-cyano- 3'-(1,5-dimethyl-4,5,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438812(4-(2-(2-((2-chloro-2′-cyano-3′-(1-meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438811(4-(2-(2-((2-chloro-2′-cyano-3′-(1-meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438809(4-((2-((3′-(5-(2-(4-carboxybicyclo[2.2.1]hep...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438808(4-(2-(2-((2'-chloro-3'-(5-(2- hydroxyethyl)-1-meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438817(4-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438806((R)-4-(2-(2-((2′-chloro-3′-(5-(2-hydro...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438805(4-(2-(2-((3'-(5-(1- carbamoylpiperidin-4-yl)-1- me...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438804(4-(2-(2-((2'-chloro-3'-(1,5- dimethyl-4,5,6,7-tetr...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438803(4-(2-(2-((2′-chloro-2-methyl-3′-(1-met...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438802(4-(2-(2-((2′-chloro-2-methyl-3′-(1-met...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438801(4-(2-(2-((3'-(5-(4- carboxyphenethyl)-1- methyl-4,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438751(4-(2-(2-((2,2′-dichloro-3′-(1-methyl-4...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM481642(4-(2-(2-((2,2′-dichloro-3′-(5-(4-hydro...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438833(4-(2-(2-((3′-(5-(trans-4-carboxy-4-methylcyc...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438832(4-(2-(2-((3′-(5-(cis-4-carboxy-4-methylcyclo...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438831(4-(2-(2-((2,2′-dichloro-3′-(5-(5-(dime...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438830(4-(2-(2-((3′-(5-(4-carboxybutyl)-1-methyl-4,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438829(4-(2-(2-((3′-(5-(2-(trans-4-carboxycyclohexy...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438827(US10618916, Example 61-(compound-1) | US10906920, ...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438827(US10618916, Example 61-(compound-1) | US10906920, ...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM481642(4-(2-(2-((2,2′-dichloro-3′-(5-(4-hydro...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438800(4-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1]heptan- ...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438824(4-(2-(2-((3'-(5-(2- hydroxyethyl)-1-methyl- 4,5,6,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438823((S)-4-(2-(2-((3'-(5-(2- hydroxypropyl)-1-methyl- 4...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438822((R)-4-(2-(2-((3′-(5-(2-hydroxypropyl)-1-meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438821(4-(2-(2-((2,2'-dimethyl-3'- (1-methyl-5-(tetrahydr...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438820(4-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438819(4,4′-(((((2,2′-dimethyl-[1,1′-bi...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438818(4-(2-(2-((2,2′-dimethyl-3′-(1-methyl-4...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438767(4-(2-(2-((3'-(5-((1H- pyrazol-3-yl)methyl)-1- meth...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438799(4,4′-(((((2-chloro-2′-methyl-[1,1̸...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438776(4,4′-(((((2,2′-dichloro-[1,1′-bi...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438775(4-(2-(2-((2,2'-dichloro-3'-(5- (3-hydroxypropyl)-1...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438774(4-(2-(2-((2,2'-dichloro-3'-(5- (2-hydroxyethyl)-1-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM565488(US11414433, Example 14 | (S)-4-(2-(2-((2,2'-dichlo...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438772((R)-4-(2-(2-((2,2′-dichloro-3′-(5-(2-h...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438771((S)-4-(2-(2-((2,2'-dichloro- 3'-(5-(2,3- dihydroxy...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438768(4-(2-(2-((2,2'-dichloro-3'-(5- (1,3-dihydroxypropa...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438777(4-((2-((3'-(5-(2-(4- carboxybicyclo[2.2.1] heptan-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438766(4-(2-(2-((2,2'-dichloro-3'-(1- methyl-5-(1- sulfam...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438764(4-(2-(2-((3'-(5-(1- carbamoylpiperidin-4-yl)-1- me...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438763(4-(2-(2-((2,2'-dichloro-3'-(5- cyclobutyl-1-methyl...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438762(4-(2-(2-((2,2'-dichloro-3'-(5- isopropyl-1-methyl-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438759(4-(2-(2-((2,2'-dichloro-3'-(5- ethyl-1-methyl-4,5,...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM438756(4-(2-(2-((2,2'-dichloro-3'- (1,5-dimethyl-4,5,6,7-...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

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