Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 10701
TargetTyrosine-protein kinase JAK2(Human)
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US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 2.89nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.06nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.08nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.16nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.24nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.47nMAssay Description:JAK2 and JAK2 [V617F] Kinase Assay: In 5× Kinase Buffer A, JAK2 or JAK2 [V617F] kinase was mixed with pre-diluted compounds at different concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.78nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 4.05nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 4.05nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 4.06nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2 [V617F](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 4.55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)