Compile Data Set for Download or QSAR
Report error Found 191 Enz. Inhib. hit(s) with all data for entry = 10690
TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365023(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365025(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-phenyl-4,5-dihy...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365027(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365030(4-(3-benzyl-4,5-dihydro-3H- 1,2,2a1,5- tetraazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365032(4-(3-(4-chlorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365034(4-(3-benzyl-5-methyl-4,5- dihydro-3H-1,2,2a1,5- te...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365036(4-(3-isobutyl-4,5-dihydro- 3H-1,2,2a1,5- tetraazaa...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365038(4-(3-(4-methoxybenzyl)-4,5- dihydro-3H-1,2,2a1,5- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365040(4-(3-(3-fluoro-4- methoxybenzyl)-4,5-dihydro- 3H-1...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383226(4-(3-(4-chlorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383227(4-(3-(4-chloro-3- fluorobenzyl)-4,5-dihydro- 3H-1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365046(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383231(4-(3-benzyl-3,4-dihydro-5- thia-1,2,2a1- triazaace...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
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TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383233(4-(3-benzyl-5-ethyl-4,5- dihydro-3H-1,2,2a1,5- tet...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383240(4-(3-(4-fluorobenzyl)-4,5- dihydro-3H-1,2,2a1,5- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383242(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383245(4-(3-((6-methoxypyridin-3- yl)methyl)-4,5-dihydro3...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383251(4-(9-((benzyloxy)methyl)- 8,9-dihydro-7H-6-oxa- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383254(4-(9-(2-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383255(4-(3-(4-fluorobenzyl)-5- methyl-4,5-dihydro-3H- 1,...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM559931(US11376260, Example I-32S | 4-(3-(4-chloro-3-fluor...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383260(4-(9-(4-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383261(4-(3-benzyl-3,4-dihydro-5- oxa-1,2,2a1- triazaacen...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383264(9-(4-chlorobenzyl)-6-methyl- 4-(2-((1-methyl-1H-py...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383266(4-(3-(4-chlorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383272(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383274(4-(3-isobutyl-3,4-dihydro-5- oxa-1,2,2a1- triazaac...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383276(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM559953(US11376260, Example I-47R | 4-(9-((4-chloro-1H-pyr...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383280(US10278975, Compound I-55 R | 4-(3-(4-chlorobenzyl...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383282(4-(3-(3-fluoro-4- methoxybenzyl)-3,4-dihydro- 5-ox...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383284(4-(3-(4-methoxybenzyl)-3,4- dihydro-5-oxa-1,2,2a1-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383286(N-(1-methyl-1H-pyrazol-5- yl)-4-(3-(2-methylbutyl)...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383288(4-(3-(3,4-difluorobenzyl)-3,4- dihydro-5-oxa-1,2,2...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383280(US10278975, Compound I-55 R | 4-(3-(4-chlorobenzyl...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383294(4-(9-((4-cyclopropyl-1H- pyrazol-1-yl)methyl)-8,9-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383296(4-(3-(4-fluorobenzyl)-3,4- dihydro-5-oxa-1,2,2a1- ...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383299(4-(9-(4-fluorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365121(US9867833, Compound I-59(R) | 4-(9-(3-fluoro-4- me...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383254(4-(9-(2-chlorobenzyl)-8,9- dihydro-7H-6-oxa-1,2,2a...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365127(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365129(9-(4-methoxybenzyl)-6- methyl-4-(2-((1-methyl- 1H-...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383314(US10278975, Compound I-108 S | 4-(9-(4-fluoropheno...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM383316(9-benzyl-6-methyl-4-(2-((1- methyl-1H-pyrazol-5- y...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365146(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365146(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365153(4-(3-benzyl-4-methyl-3,4- dihydro-5-oxa-1,2,2a1- t...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365148(N-(1-methyl-1H-pyrazol-5- yl)-4-(9-((4-(trifluorom...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM560007(US11376260, Example I-73S | N-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 6(Human)
Genentech

US Patent
LigandPNGBDBM365149(9-(2-fluoro-4- methoxybenzyl)-6-methyl-4- (2-((1-m...)
Affinity DataIC50: 0.0200nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
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