Compile Data Set for Download or QSAR
Report error Found 373 Enz. Inhib. hit(s) with all data for entry = 10671
TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189797(US9174982, 371 | US9174982, 376 | US11369599, Comp...)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189799(US9174982, 373 | US10213433, Compound 373 | US1136...)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189800(US9174982, 374 | US10213433, Compound 374 | US1136...)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189797(US9174982, 371 | US9174982, 376 | US11369599, Comp...)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189803(US9174982, 377 | US11369599, Compound 377)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189804(US9174982, 378 | US10213433, Compound 378 | US1136...)
Affinity DataKi: <0.00100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189567(US9174982, 129 | US10213433, Compound 129 | US1136...)
Affinity DataKi:  0.00200nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189456(US9174982, 2 | US10213433, Compound 2 | US11369599...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189628(US9174982, 191 | US10213433, Compound 191 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189629(US9174982, 192 | US10213433, Compound 192 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189458(US9174982, 4 | US10213433, Compound 4 | US11369599...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189630(US9174982, 193 | US10213433, Compound 193 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM60828(BDBM189459 | US9174982, 369 | ABT-199 | US10213433...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189631(US9174982, 194 | US10213433, Compound 194 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356813(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189558(US9174982, 120 | US10213433, Compound 196 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189634(US9174982, 197 | US10213433, Compound 197 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356627(trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189635(US9174982, 198 | US9174982, 200 | US9174982, 199 |...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189464(US9174982, 10 | US10213433, Compound 10 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356817(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356817(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189466(US9174982, 12 | US10213433, Compound 12 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189467(US9174982, 13 | US10213433, Compound 13 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189638(US9174982, 202 | US10213433, Compound 202 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356821(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189469(US9174982, 15 | US10213433, Compound 15 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356822(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189639(US9174982, 205 | US10213433, Compound 205 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356827(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189472(US9174982, 24 | US10213433, Compound 24 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM60820(US9174982, 213 | US10213433, Compound 213 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189473(US9174982, 25 | US10213433, Compound 25 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189647(US9174982, 214 | US10213433, Compound 214 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189648(US9174982, 215 | US10213433, Compound 215 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189649(US9174982, 216 | US10213433, Compound 216 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189476(US9174982, 28 | US10213433, Compound 28 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189650(US9174982, 217 | US10213433, Compound 217 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356647(cis-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189478(US9174982, 30 | US10213433, Compound 30 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189479(US9174982, 31 | US10213433, Compound 31 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189480(US9174982, 32 | US10213433, Compound 32 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356651(trans-4-(4-{[4-(4-chlorophenyl)-6,6-dimethyl-5,6-d...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356652(trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...)
Affinity DataKi:  0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189483(US9174982, 35 | US10213433, Compound 35 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM356842(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189485(US9174982, 37 | US10213433, Compound 37 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189659(US9174982, 227 | US10213433, Compound 227 | US1136...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189488(US9174982, 40 | US10213433, Compound 40 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetApoptosis regulator Bcl-2(Human)
Abbvie

US Patent
LigandPNGBDBM189489(US9174982, 41 | US10213433, Compound 41 | US113695...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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