Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 10611
TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.0400nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554464(US11332479, Compound 50III)
Affinity DataIC50: 0.0500nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554470(US11332479, Compound 72IV)
Affinity DataIC50: 0.0800nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554462(US11332479, Compound 46III)
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554469(US11332479, Compound 70IV)
Affinity DataIC50: 0.150nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554471(US11332479, Compound 73IV)
Affinity DataIC50: 0.160nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554463(US11332479, Compound 48III)
Affinity DataIC50: 0.270nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554467(US11332479, Compound 64IV)
Affinity DataIC50: 0.360nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554460(US11332479, Compound 42III)
Affinity DataIC50: 0.360nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554468(US11332479, Compound 65IV)
Affinity DataIC50: 0.370nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.670nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435718(US10570155, Compound 2II | US11332479, Compound 2I...)
Affinity DataIC50: 0.75nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554457(US11332479, Compound 31II)
Affinity DataIC50: 0.980nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435721(US10570155, Compound 25III | US11332479, Compound ...)
Affinity DataIC50: 1nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554465(US11332479, Compound 52III)
Affinity DataIC50: 1.03nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554458(US11332479, Compound 37III)
Affinity DataIC50: 1.66nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 1.85nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554459(US11332479, Compound 38III)
Affinity DataIC50: 1.89nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 2.58nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554465(US11332479, Compound 52III)
Affinity DataIC50: 2.68nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 2.95nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 2.96nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435711(US10570155, Compound 1II | US11332479, Compound 1I...)
Affinity DataIC50: 3.23nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554457(US11332479, Compound 31II)
Affinity DataIC50: 4.19nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554465(US11332479, Compound 52III)
Affinity DataIC50: 5.41nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435721(US10570155, Compound 25III | US11332479, Compound ...)
Affinity DataIC50: 5.70nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554461(US11332479, Compound 43III)
Affinity DataIC50: 6.96nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554457(US11332479, Compound 31II)
Affinity DataIC50: 7.83nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50289149(GW305074X | US10570155, GW5074 | GW5074 | US113324...)
Affinity DataIC50: 8.52nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554458(US11332479, Compound 37III)
Affinity DataIC50: 8.80nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554466(US11332479, Compound 60IV)
Affinity DataIC50: 11.3nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM554458(US11332479, Compound 37III)
Affinity DataIC50: 13.8nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 31nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [696-1022,L858R](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 48nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435719(US10570155, Compound 2III | US11332479, Compound 2...)
Affinity DataIC50: 77nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435720(US10570155, Compound 8III | US11332479, Compound 8...)
Affinity DataIC50: 98nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataIC50: 100nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435719(US10570155, Compound 2III | US11332479, Compound 2...)
Affinity DataIC50: 459nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science and Technology

US Patent
LigandPNGBDBM435720(US10570155, Compound 8III | US11332479, Compound 8...)
Affinity DataIC50: 687nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
Go to US Patent