Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 10599
TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458518(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 2nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458524(5-chloro-2-fluoro-4-((6-fluoro-2-((isopropyl(methy...)
Affinity DataIC50: 12nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458508(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 15nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458525(2-fluoro-4-((6-fluoro-2-((isopropyl(methyl)amino)m...)
Affinity DataIC50: 16nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458515(2,6-difluoro-4-((6-fluoro-3-isopropoxy-2-((isoprop...)
Affinity DataIC50: 26nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458516(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 26nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458509(2,6-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 27nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458517(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-3,6...)
Affinity DataIC50: 28nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458523(2,3-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 31nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458511(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 47nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458519(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 54nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458513(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 95nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458510(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 142nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458514(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 181nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458520(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 270nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458522(US10745392, Example 15a | US11325902, Example 15a)
Affinity DataIC50: 530nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458512(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 617nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458521(4-((2-(1-(7-azabicyclo[2.2.1]heptan-7-yl)ethyl)-3,...)
Affinity DataIC50: 653nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458526(US10745392, Example 15b | US11325902, Example 15b)
Affinity DataIC50: 821nMAssay Description:The following patch voltage clamp electrophysiology studies may be performed on representative compounds of the invention using human embryonic kidne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458513(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 5.23E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458518(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 5.91E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458514(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 7.44E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458516(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 7.85E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458517(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-3,6...)
Affinity DataIC50: 7.93E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458523(2,3-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 9.46E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458508(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 9.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458515(2,6-difluoro-4-((6-fluoro-3-isopropoxy-2-((isoprop...)
Affinity DataIC50: 1.11E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458525(2-fluoro-4-((6-fluoro-2-((isopropyl(methyl)amino)m...)
Affinity DataIC50: 1.18E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458521(4-((2-(1-(7-azabicyclo[2.2.1]heptan-7-yl)ethyl)-3,...)
Affinity DataIC50: 1.28E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458513(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 1.53E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458524(5-chloro-2-fluoro-4-((6-fluoro-2-((isopropyl(methy...)
Affinity DataIC50: 1.63E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458511(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458516(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 2.04E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458514(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 2.13E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458520(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 2.37E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458517(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-3,6...)
Affinity DataIC50: 2.54E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458518(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 2.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458509(2,6-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 2.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458515(2,6-difluoro-4-((6-fluoro-3-isopropoxy-2-((isoprop...)
Affinity DataIC50: 2.80E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458509(2,6-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 2.83E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458526(US10745392, Example 15b | US11325902, Example 15b)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458525(2-fluoro-4-((6-fluoro-2-((isopropyl(methyl)amino)m...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458526(US10745392, Example 15b | US11325902, Example 15b)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458523(2,3-difluoro-4-((6-fluoro-2-((isopropyl(methyl)ami...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458524(5-chloro-2-fluoro-4-((6-fluoro-2-((isopropyl(methy...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458522(US10745392, Example 15a | US11325902, Example 15a)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458522(US10745392, Example 15a | US11325902, Example 15a)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458521(4-((2-(1-(7-azabicyclo[2.2.1]heptan-7-yl)ethyl)-3,...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458520(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

TargetSodium channel protein type 1 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM458519(4-((2-((7-azabicyclo[2.2.1]heptan-7-yl)methyl)-6-f...)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
Go to US Patent

Displayed 1 to 50 (of 57 total ) | Next | Last >>
Jump to: