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Compile Data Set for Download or QSAR
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Found
12
Enz. Inhib. hit(s) with all data for entry = 10452
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536306
(3-(2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl...)
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Copy InChI
Affinity Data
IC50: 1.5nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536304
((E)-2-(5-((4-(2-hydroxyethyl)piperidin-1-yl)sulfon...)
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Copy InChI
Affinity Data
IC50: 1.60nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536316
(2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1-yl)...)
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Affinity Data
IC50: 2.80nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536307
(2-(2-ethoxy-5-((4-(2-hydroxyethyl)piperazin-1-yl)s...)
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Copy InChI
Affinity Data
IC50: 4.10nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536314
((E)-2-(2-ethoxy-5-((4-(3-hydroxypropyl)piperazin-1...)
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Copy InChI
Affinity Data
IC50: 4.20nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536310
((E)-2-(2-ethoxy-5-((4-(2-hydroxyethyl)piperidin-1-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.80nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536303
((E)-5-methyl-2-(5-((4-methylpiperazin-1-yl)sulfony...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.30nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM14390
(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
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Affinity Data
IC50: 5.40nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
PDB
3D Structure (crystal)
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Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536315
((E)-3-(4-((4-ethoxy-3-(6-((hydroxyimino)methyl)-5-...)
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Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536302
(2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)ph...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536301
((E)-2-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfony...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 25nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human)
Topadur Pharma
US Patent
Ligand
BDBM536313
((E)-2-(1-((4-ethoxy-3-(6-((hydroxyimino)methyl)-5-...)
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Copy InChI
Affinity Data
IC50: 66nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/10/2022
Entry Details
Copy Entry DOI
Go to US Patent
Copy Rxn URL