Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 10414
TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533749(US11225492, Compound 12 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533760(US11225492, Compound 18 | Preparation of 6-((6-ace...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533755(US11225492, Compound 16 | Preparation of 4-((4-(6-...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533749(US11225492, Compound 12 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533755(US11225492, Compound 16 | Preparation of 4-((4-(6-...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533754(US11225492, Compound 15 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533751(US11225492, Compound 14 | Preparation of 7-(4-(6-(...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533751(US11225492, Compound 14 | Preparation of 7-(4-(6-(...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533586(US11225492, Compound 1 | 2-(5-(3,7-diazabicyclo[3....)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533742(US11225492, Compound 8 | Preparation of 6-acetyl-8...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533741(US11225492, Compound 7S)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533740(US11225492, Compound 7R)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533739(US11225492, Compound 7)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533738(US11225492, Compound 6)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533737(US11225492, Compound 5 | Preparation of 2-(5-(3,9-...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533726(US11225492, Compound 3 | 2-(5-(2,7-Diazaspiro[3.5]...)
Affinity DataIC50: 10nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533586(US11225492, Compound 1 | 2-(5-(3,7-diazabicyclo[3....)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533621(US11225492, Compound 2 | 2-(5-(9-oxa-3,7-diazabicy...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533754(US11225492, Compound 15 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533726(US11225492, Compound 3 | 2-(5-(2,7-Diazaspiro[3.5]...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533750(US11225492, Compound 13 | Preparation of 5-(4-(6-(...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533749(US11225492, Compound 12 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533727(US11225492, Compound 4-1)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533741(US11225492, Compound 7S)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533737(US11225492, Compound 5 | Preparation of 2-(5-(3,9-...)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533739(US11225492, Compound 7)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533740(US11225492, Compound 7R)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533738(US11225492, Compound 6)
Affinity DataIC50: 25nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533755(US11225492, Compound 16 | Preparation of 4-((4-(6-...)
Affinity DataIC50: 50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533760(US11225492, Compound 18 | Preparation of 6-((6-ace...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533757(US11225492, Compound 17 | Preparation of 6-((6-ace...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533754(US11225492, Compound 15 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533751(US11225492, Compound 14 | Preparation of 7-(4-(6-(...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533749(US11225492, Compound 12 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 50nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533760(US11225492, Compound 18 | Preparation of 6-((6-ace...)
Affinity DataIC50: 50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533757(US11225492, Compound 17 | Preparation of 6-((6-ace...)
Affinity DataIC50: 50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533728(US11225492, Compound 4-2)
Affinity DataIC50: 50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533750(US11225492, Compound 13 | Preparation of 5-(4-(6-(...)
Affinity DataIC50: 50nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533727(US11225492, Compound 4-1)
Affinity DataIC50: 100nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533728(US11225492, Compound 4-2)
Affinity DataIC50: 100nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533621(US11225492, Compound 2 | 2-(5-(9-oxa-3,7-diazabicy...)
Affinity DataIC50: 100nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533742(US11225492, Compound 8 | Preparation of 6-acetyl-8...)
Affinity DataIC50: 100nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533757(US11225492, Compound 17 | Preparation of 6-((6-ace...)
Affinity DataIC50: 500nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533755(US11225492, Compound 16 | Preparation of 4-((4-(6-...)
Affinity DataIC50: 500nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533754(US11225492, Compound 15 | Preparation of 8-(4-(6-(...)
Affinity DataIC50: 500nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533757(US11225492, Compound 17 | Preparation of 6-((6-ace...)
Affinity DataIC50: 500nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533751(US11225492, Compound 14 | Preparation of 7-(4-(6-(...)
Affinity DataIC50: 500nMAssay Description:The inhibitory effect of compounds on HDAC-1, HDAC-2 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533760(US11225492, Compound 18 | Preparation of 6-((6-ace...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533740(US11225492, Compound 7R)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM533727(US11225492, Compound 4-1)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

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