Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 10384
TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532308(JDM666A | N-(2,6-dimethylphenyl-2-[4-[4-[2-ethylam...)
Affinity DataIC50: 0.410nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532304(JDM697A | N-[1-[2-(2-ethoxyethoxy)ethyl]-3,5-dieth...)
Affinity DataIC50: 0.410nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532306(JDM703A | N-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)...)
Affinity DataIC50: 0.430nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532294(JDM0684A | N-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy...)
Affinity DataIC50: 0.430nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532285(WITJ113B | N-(2,6-diethylphenyl)-8-(2-methoxy-4-pi...)
Affinity DataIC50: 0.490nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM258443(US9512130, 1 | US11208696, Example 6)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532289(JGS439C | N-(2,6-dimethylphenyl)-2-[2-methoxy-4-(t...)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532292(JGS79C | N-(2,6-diethylphenyl)-2-[2-methoxy-4-(4-m...)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532301(JDM677A | N-[1-[2-[2-(2-methoxyethoxy)ethoxyethyl]...)
Affinity DataIC50: 0.620nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM50349102(CHEMBL1236095 | US11208696, Example 3)
Affinity DataIC50: 0.630nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM258445(US9512130, 3 | US11208696, Example 5)
Affinity DataIC50: 0.650nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532307(JDM709A | 2-[4-[4-[(2R)-azetidine-2-carbonyl]piper...)
Affinity DataIC50: 0.660nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532288(WITJ0416/WITJ429A | N-(2,6-dimethylphenyl)-2-(2-me...)
Affinity DataIC50: 0.700nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532303(JDM713A | N-[3,5-diethyl-1-[2-(2-methoxyethoxy)eth...)
Affinity DataIC50: 0.710nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532290(JDM0641A | N-[1-[2-[2-(2-methoxyethoxyethoxy]ethyl...)
Affinity DataIC50: 0.730nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532309(JGS0715B | N-cyclopropyl-4-[6-(2,3-difluoro-4-meth...)
Affinity DataIC50: 0.790nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532305(JDM636A | N-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)...)
Affinity DataIC50: 0.910nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532291(JDM0443A | N-[1-[2-[2-(2-methoxyethoxy)ethoxy]ethy...)
Affinity DataIC50: 0.930nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532302(JDM711A | N-[3,5-diethyl-1-[2-(2-methoxyethoxy eth...)
Affinity DataIC50: 0.960nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532293(WITJ453B | N-(3,5-diethyl-1H-pyrazol-4-yl)-2-[2-(d...)
Affinity DataIC50: 0.970nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532295(JDM0466A | N-[3,5-diethyl-1-[2-(2-methoxy)ethyl]py...)
Affinity DataIC50: 0.980nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532298(WITJ0529B | N-(2,6-dimethylphenyl)-2-[2-methoxy-4-...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532297(JDM323A | N-(3,5-dimethyl-1H-pyrazol-4-≡(1-2...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532296(WITJ349B | N-[1-(2-m ethoxy yl-3,5-dimethyl-pyrazo...)
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532300(JDM640A | N-[1-[2-(2-ethoxyethoxy)ethyl]-3,5-dimet...)
Affinity DataIC50: 1.14nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532299(WITJ490B | N-(2,6-dimethylphenyl)-2-[2-methoxy-4-[...)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM329334((2R)-2-(4-fluorophenyl)-N-[4-(2-{[2-methoxy-4-(met...)
Affinity DataIC50: 2.55nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532282(WITJ0018D | N6-cyclohexyl-N2-(2-methyl-4-morpholin...)
Affinity DataIC50: 2.60nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM50072833(CHEMBL3410060 | US11208696, Example 2)
Affinity DataIC50: 4.10nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM50420401(CHEMBL2089255 | US11208696, Example 31)
Affinity DataIC50: 7nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM36485(1-(4-(4-(2-(Isopropylsulfonyl)phenylamino)-1H-pyrr...)
Affinity DataIC50: 37.5nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent