Compile Data Set for Download or QSAR
Report error Found 111 Enz. Inhib. hit(s) with all data for entry = 10072
TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439415((S)-4-(4-(tert-butoxy)-2-(4-(5-chloro-2-propionylp...)
Affinity DataIC50: 12nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439331((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 13nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439330((S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy...)
Affinity DataIC50: 14nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439325((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 16nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439328(4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-o...)
Affinity DataIC50: 17nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439418((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 18nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439322((S)-5-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 19nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439344((S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy...)
Affinity DataIC50: 21nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439373((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 21nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439396((S)-4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy...)
Affinity DataIC50: 21nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439408((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 23nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439340(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 24nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439398((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 24nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439421((S)-4-(tert-butoxy)-2-(4-(5-chloro-2-propionylphen...)
Affinity DataIC50: 27nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439415((S)-4-(4-(tert-butoxy)-2-(4-(5-chloro-2-propionylp...)
Affinity DataIC50: 27nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439349((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 29nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439405(4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-o...)
Affinity DataIC50: 29nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439350(N-(1H-benzo[d]imidazol-5-yl)-2-(4-(5-chloro-2-prop...)
Affinity DataIC50: 30nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439414((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 30nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439447((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 30nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439325((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 31nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439401(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50: 32nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439420(4-(tert-butoxy)-2-(4-(5-chloro-2-propionylphenyl)-...)
Affinity DataIC50: 33nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439438(4-(2-(4-(6-acetyl-3-chloro-2-fluorophenyl)-5-metho...)
Affinity DataIC50: 33nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439321(5-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 34nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439327(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 34nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439364(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 34nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439365(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 35nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439406(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 35nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439444(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 35nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439451((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 35nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439338((S)-2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxo...)
Affinity DataIC50: 36nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439339(4-(2-(4-(2-butyryl-5-chlorophenyl)-5-methoxy-2-oxo...)
Affinity DataIC50: 36nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439341(4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-o...)
Affinity DataIC50: 36nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439403(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50: 36nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439432(4-(2-(4-(6-acetyl-3-chloro-2-fluorophenyl)-5-metho...)
Affinity DataIC50: 37nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439351(4-(2-(4-(5-chloro-2-(2-cyclopropylacetyl)phenyl)-5...)
Affinity DataIC50: 38nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439352(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50: 38nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439324(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 39nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
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TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439353(4-(2-(4-(5-chloro-2-(cyclopropanecarbonyl)phenyl)-...)
Affinity DataIC50: 39nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439354(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50: 40nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439380((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 40nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439404(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxopyri...)
Affinity DataIC50: 40nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439332(methyl (S)-(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-me...)
Affinity DataIC50: 42nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439384((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 42nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439393((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 42nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439397(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 42nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439448(4-(2-(4-(5-chloro-2-propionylphenyl)-5-methoxy-2-o...)
Affinity DataIC50: 42nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439363(4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50: 43nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM439450((S)-4-(2-(4-(2-acetyl-5-chlorophenyl)-5-methoxy-2-...)
Affinity DataIC50: 43nMAssay Description:1. Experimental MaterialsEnzyme: Coagulation Factor XIa protease (Abcam, Art. No ab62411)Substrate: Coagulation Factor XIa specific substrate (HYPHEN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/24/2022
Entry Details
Go to US Patent

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