Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 9885
TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103737(US8563545, 11 | US10206907, Compound 234 | US11000...)
Affinity DataIC50: 7.69nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103737(US8563545, 11 | US10206907, Compound 234 | US11000...)
Affinity DataIC50: 15.5nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103736(US8563545, 10 | US10206907, Compound 207 | US11000...)
Affinity DataIC50: 18.2nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 31.4nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103728(US8563545, 2 | US10206907, Compound 18 | US1100052...)
Affinity DataIC50: 38.7nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 47.1nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103728(US8563545, 2 | US10206907, Compound 18 | US1100052...)
Affinity DataIC50: 50.9nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103736(US8563545, 10 | US10206907, Compound 207 | US11000...)
Affinity DataIC50: 65.4nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 72.7nMAssay Description:Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) was purchased from Carna biosciences. 5 ng of TYK2 was incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
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LigandPNGBDBM103737(US8563545, 11 | US10206907, Compound 234 | US11000...)
Affinity DataIC50: 126nMAssay Description:Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) was purchased from Carna biosciences. 5 ng of TYK2 was incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandPNGBDBM103727(US8563545, 1 | US10112907, Example 00033 | US10206...)
Affinity DataIC50: 149nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandPNGBDBM103737(US8563545, 11 | US10206907, Compound 234 | US11000...)
Affinity DataIC50: 195nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103729(US8563545, 3 | US10206907, Compound 2 | US11000528...)
Affinity DataIC50: 291nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103735(US8563545, 9 | US10206907, Compound 141 | US110005...)
Affinity DataIC50: 334nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103734(US8563545, 8 | US10206907, Compound 140 | US110005...)
Affinity DataIC50: 435nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103733(US8563545, 7 | US10206907, Compound 139 | US110005...)
Affinity DataIC50: 504nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103735(US8563545, 9 | US10206907, Compound 141 | US110005...)
Affinity DataIC50: 849nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103730(US8563545, 4 | US10206907, Compound 6 | US11000528...)
Affinity DataIC50: 1.03E+3nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103731(US8563545, 5 | US10206907, Compound 129 | US110005...)
Affinity DataIC50: 1.45E+3nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103731(US8563545, 5 | US10206907, Compound 129 | US110005...)
Affinity DataIC50: 1.76E+3nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

LigandPNGBDBM103728(US8563545, 2 | US10206907, Compound 18 | US1100052...)
Affinity DataIC50: 2.10E+3nMAssay Description:Recombinant human TYK2 catalytic domain (amino acids 871-1187; catalog number 08-147) was purchased from Carna biosciences. 5 ng of TYK2 was incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Galapagos

US Patent
LigandPNGBDBM103728(US8563545, 2 | US10206907, Compound 18 | US1100052...)
Affinity DataIC50: 2.84E+3nMAssay Description:Recombinant human JAK3 catalytic domain (amino acids 781-1124; catalog number PV3855) was purchased from Invitrogen. 0.025 mU of JAK3 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103732(US8563545, 6 | US10206907, Compound 130 | US110005...)
Affinity DataIC50: 3.45E+3nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103732(US8563545, 6 | US10206907, Compound 130 | US110005...)
Affinity DataIC50: 5.07E+3nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103733(US8563545, 7 | US10206907, Compound 139 | US110005...)
Affinity DataIC50: 6.45E+3nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Galapagos

US Patent
LigandPNGBDBM103734(US8563545, 8 | US10206907, Compound 140 | US110005...)
Affinity DataIC50: 7.73E+3nMAssay Description:Recombinant human JAK2 catalytic domain (amino acids 808-1132; catalog number PV4210) was purchased from Invitrogen. 0.025 mU of JAK2 was incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
Go to US Patent