Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 9744
TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50: 500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350111(US10208043, # 12 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350102(US10208043, # 3 | 2-chloro-N-(6- chlorobenzo[d]thi...)
Affinity DataIC50: 652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350107(US10208043, # 8 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350100(US10208043, # 1 | 5-(3,4-dichlorobenzyl)-1- (S,S,-...)
Affinity DataIC50: 734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350109(US10208043, # 10 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350110(US10208043, # 11 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350120(US10208043, # 21 | 5-(3-chlorobenzyl)-1-(2- hydrox...)
Affinity DataIC50: 1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350108(US10208043, # 9 | N-(3-(1H-1,2,4-triazol-3- ylthio...)
Affinity DataIC50: 1.47E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350101(US10208043, # 2 | N-(1-(4- (trifluoromethyl)benzyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350112(US10208043, # 13 | (Z)-N-(3-(1H-1,2,4-triazol- 3-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350128(US10208043, # 30 | 5-(3,4-dichlorobenzyl)-1- o-tol...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350118(US10208043, # 19 | N-(6- chlorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350130(US10208043, # 32 | 5-(3,4-dichlorobenzyl)-1- (2,4-...)
Affinity DataIC50: 2.10E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350129(US10208043, # 31 | 5-(3,4-dichlorobenzyl)-1- (2,3-...)
Affinity DataIC50: 2.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50: 2.62E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350114(US10208043, # 15 | N-(3-(1H-1,2,4-triazol-3- ylthi...)
Affinity DataIC50: 2.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350121(US10208043, # 23 | 2-(4-oxo-1-(S,S,-dioxo- tetrahy...)
Affinity DataIC50: 3.40E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350127(US10208043, # 29 | 5-(2-(benzo[d][1,3]dioxol- 5-yl...)
Affinity DataIC50: 3.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350116(US10208043, # 17 | N-(6- fluorobenzo[d]thiazol-2- ...)
Affinity DataIC50: 4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350115(US10208043, # 16 | 3-chloro-N-(6- phenoxybenzo[d]t...)
Affinity DataIC50: 4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350119(US10208043, # 20 | N-(benzo[d]thiazol-2- yl)cinnam...)
Affinity DataIC50: 4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350122(US10208043, # 24 | N-(4-fluorobenzyl)-2-(4- oxo-1-...)
Affinity DataIC50: 4.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM485822(N-(4-chlorophenyl)-2-(4- oxo-1-(S,S-dioxo- tetrahy...)
Affinity DataIC50: 4.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350123(US10208043, # 25 | N-(benzo[d][1,3]dioxol-5- ylmet...)
Affinity DataIC50: 4.60E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350126(US10208043, # 28 | 5-(2-(2,4-dimethylphenyl)- 2-ox...)
Affinity DataIC50: 4.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350105(US10208043, # 6 | N-benzyl-2,3-diphenyl- 1,2,4-thi...)
Affinity DataIC50: 5.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350125(US10208043, # 27 | 5-(2-(2,3- dihydrobenzo[b][1,4]...)
Affinity DataIC50: 1.00E+4nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent

TargetFascin(Human)
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350117(US10208043, # 18 | 2,3-dichloro-N-(6- fluorobenzo[...)
Affinity DataIC50: 1.30E+4nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent