Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 9742
TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485688(US10941129, Example 20)
Affinity DataIC50: 2.48nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485698(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-cya...)
Affinity DataIC50: 3.16nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485690(N-hydroxylethyl-4-(2-bromo-3-phenylbenzyloxy)-5-ch...)
Affinity DataIC50: 5.29nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485703(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-met...)
Affinity DataIC50: 10nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485701(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-met...)
Affinity DataIC50: 10nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485699(US10941129, Example 26)
Affinity DataIC50: 10nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485686(N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-...)
Affinity DataIC50: 18.1nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485679(US10941129, Example 2)
Affinity DataIC50: 29.4nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485684(N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-...)
Affinity DataIC50: 38.5nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485683(US10941129, Example 4)
Affinity DataIC50: 59.2nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM470337(US10815208, Example 2 | US10941129, Example 22)
Affinity DataIC50: 62.3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485696((S) N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxi...)
Affinity DataIC50: 67.5nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485691(US10941129, Example 8)
Affinity DataIC50: 134nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485687(US10941129, Example 6)
Affinity DataIC50: 178nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485681(N-Ethyl-N-hydroxylethyl-4-(2-bromo-3-phenylbenzylo...)
Affinity DataIC50: 230nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485680(N-acetylaminoethyl-4-(2-bromo-3-(2,3-dihydrobenzo[...)
Affinity DataIC50: 268nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485685(N-hydroxylethyl-4-(2-bromo-3-phenylbenzyloxy)-2-(3...)
Affinity DataIC50: 307nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485678(N-acetylaminoethyl-4-(2-bromo-3-phenylbenzyloxy)-2...)
Affinity DataIC50: 439nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485695(US10941129, Example 10)
Affinity DataIC50: 458nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485693(N-(tetrahydro-2H-pyran-4-yl)-4-(2-bromo-3-phenylbe...)
Affinity DataIC50: 788nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485694(N-(2-methanesulfonylaminoethyl)-4-(2-bromo-3-pheny...)
Affinity DataIC50: 979nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485682(N-(4-(2-bromo-3-(3,4-dimethoxyphenyl)benzyloxy)-2-...)
Affinity DataIC50: 3.16E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485689(US10941129, Example 7)
Affinity DataIC50: 4.59E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485700(N-(4-(2-bromo-3-(3,4-dimethoxyphenyl)benzyloxy)-2-...)
Affinity DataIC50: 5.35E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485702(N-acetylaminoethyl-4-(2-bromo-3-(3,4-dimethoxyphen...)
Affinity DataIC50: 6.65E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485697(N-hydroxylethyl-4-(2-bromo-3-(3,4-dimethoxyphenyl)...)
Affinity DataIC50: 7.87E+3nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
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