Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 9718
TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483551(US10927086, Example 25 | N-((S)-4-fluorobicyclo[4....)
Affinity DataIC50: 31.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483621(US10927086, Example 76 | US10927086, Example 77 | ...)
Affinity DataIC50: 34.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483551(US10927086, Example 25 | N-((S)-4-fluorobicyclo[4....)
Affinity DataIC50: 35.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483539(US10927086, Example 11)
Affinity DataIC50: 38.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483621(US10927086, Example 76 | US10927086, Example 77 | ...)
Affinity DataIC50: 40nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483553(US10927086, Example 27 | US10927086, Example 28 | ...)
Affinity DataIC50: 43.3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483538(US10927086, Example 8)
Affinity DataIC50: 43.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483635(N-((S)-4-fluorobicyclo[4.2.0]octa-1(6),2,4-trien-7...)
Affinity DataIC50: 44.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483629(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 46.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483565(US10927086, Example 39 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 47.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483640(N-((S)-4-fluorobicyclo[4.2.0]octa-1(6),2,4-trien-7...)
Affinity DataIC50: 47.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483629(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 47.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483610(4-{[3-(S- aminosulfonimidoyl)propyl]amino}-N- [(7S...)
Affinity DataIC50: 48.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483540(2-((4-(N-((S)-4- fluorobicyclo[4.2.0]octa-1(6),2,4...)
Affinity DataIC50: 49.3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483617(US10927086, Example 73 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 49.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483629(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 49.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483565(US10927086, Example 39 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 50.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483638(N—((S)-4-fluorobicyclo[4.2.0]octa-1(6),2,4-tr...)
Affinity DataIC50: 51nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483553(US10927086, Example 27 | US10927086, Example 28 | ...)
Affinity DataIC50: 53.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483544(US10927086, Example 16 | 4-((2-(N-carbamoyl-S- met...)
Affinity DataIC50: 55.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483629(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 56.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483569(US10927086, Example 42 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 56.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483623(US10927086, Example 80 | US10927086, Example 79 | ...)
Affinity DataIC50: 57.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483540(2-((4-(N-((S)-4- fluorobicyclo[4.2.0]octa-1(6),2,4...)
Affinity DataIC50: 58.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483613(4-{[2-(S- cyclopropylsulfonimidoyl)ethyl]amino}- N...)
Affinity DataIC50: 59.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483561(4-{[2-(N,S- dimethylsulfonimidoyl)ethyl]amino}-N- ...)
Affinity DataIC50: 59.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483553(US10927086, Example 27 | US10927086, Example 28 | ...)
Affinity DataIC50: 60.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483611(US10927086, Example 67 | 4-({2-[(N,S- dimethylsulf...)
Affinity DataIC50: 63.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483540(2-((4-(N-((S)-4- fluorobicyclo[4.2.0]octa-1(6),2,4...)
Affinity DataIC50: 63.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483617(US10927086, Example 73 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 63.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483613(4-{[2-(S- cyclopropylsulfonimidoyl)ethyl]amino}- N...)
Affinity DataIC50: 64.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483545(US10927086, Example 17 | 4-((2-(N-cyano-S- methyls...)
Affinity DataIC50: 64.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483546(US10927086, Example 18 | N-((S)-4-fluorobicyclo[4....)
Affinity DataIC50: 67.2nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483546(US10927086, Example 18 | N-((S)-4-fluorobicyclo[4....)
Affinity DataIC50: 68.3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483588(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 69.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483553(US10927086, Example 27 | US10927086, Example 28 | ...)
Affinity DataIC50: 70.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483594(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 70.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483619(US10927086, Example 75 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 73.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483623(US10927086, Example 80 | US10927086, Example 79 | ...)
Affinity DataIC50: 77.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483615(US10927086, Example 71 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 79.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483615(US10927086, Example 71 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 80nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483611(US10927086, Example 67 | 4-({2-[(N,S- dimethylsulf...)
Affinity DataIC50: 80.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483627(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 81.5nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483561(4-{[2-(N,S- dimethylsulfonimidoyl)ethyl]amino}-N- ...)
Affinity DataIC50: 81.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483603(N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-...)
Affinity DataIC50: 81.6nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483607(US10927086, Example 63 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 83nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483563(US10927086, Example 36 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 85.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483535(US10927086, Example 1 | N—((S)-4-fluorobicycl...)
Affinity DataIC50: 86nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483636(N—((S)-4-fluorobicyclo[4.2.0]octa-1(6),2,4-tr...)
Affinity DataIC50: 88.1nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483619(US10927086, Example 75 | N-[(7S)-4-fluorobicyclo[4...)
Affinity DataIC50: 90.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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