Compile Data Set for Download or QSAR
Report error Found 302 Enz. Inhib. hit(s) with all data for entry = 9682
LigandPNGBDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 2nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474162(US10912773, Example 44 | 6-ethyl-7-(4-methoxybenzy...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474194(US10912773, Example 74 | 3-(6-chloro-2,3-dihydro-1...)
Affinity DataIC50: 5nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 6nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 6nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474111(US10912773, Example 4 | 7-(Cyclohexylmethyl)-6-met...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474143(US10912773, Example 33 | 7-(3-fluorobenzyl)-6-meth...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474151(US10912773, Example 36-isomer-3 | 7-(3-fluorobenzy...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474197(US10912773, Example 77 | 3-isopropyl-7-(4-methoxyb...)
Affinity DataIC50: 7nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474125(US10912773, Example 18 | 7-(3-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474146(US10912773, Example 35-isomer-3 | 7-(3-fluorobenzy...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474189(US10912773, Example 69 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474124(US10912773, Example 17 | 7-(2-Fluorobenzyl)-6-meth...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474132(US10912773, Example 25 | 6-Methyl-7-(3-methylbenzy...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474161(US10912773, Example 43 | 7-benzyl-6-ethyl-3-(tetra...)
Affinity DataIC50: 9nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474126(US10912773, Example 19 | 7-(2-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474172(US10912773, Example 55-isomer-1 | 7-(4-methoxybenz...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474184(US10912773, Example 65 | 7-(cycloheptylmethyl)-6-m...)
Affinity DataIC50: 10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474109(US10912773, Example 2 | 6-Benzyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474111(US10912773, Example 4 | 7-(Cyclohexylmethyl)-6-met...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474212(US10912773, Example 92 | 6-(cyclopentylmethyl)-7-(...)
Affinity DataIC50: 11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474110(US10912773, Example 3 | 6-Benzyl-7-(cyclohexylmeth...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474123(US10912773, Example 16 | 7-Benzyl-6-methyl-3-(tetr...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474130(US10912773, Example 23 | 7-(4-Methoxybenzyl)-6-met...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474171(US10912773, Example 54 | 6-ethyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474192(US10912773, Example 72 | (R)-7-(4-methoxybenzyl)-6...)
Affinity DataIC50: 12nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM480842(US10905688, Example 55, isomer 3 | 7-(4-methoxyben...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474189(US10912773, Example 69 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474197(US10912773, Example 77 | 3-isopropyl-7-(4-methoxyb...)
Affinity DataIC50: 13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474109(US10912773, Example 2 | 6-Benzyl-7-(3-fluorobenzyl...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474112(US10912773, Example 5 | 7-(3-Fluorobenzyl)-6-methy...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474130(US10912773, Example 23 | 7-(4-Methoxybenzyl)-6-met...)
Affinity DataIC50: 14nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474121(US10912773, Example 14 | 7-(4-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474122(US10912773, Example 15 | 6-Bromo-7-(3-fluorobenzyl...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474149(US10912773, Example 36-isomer-1 | 7-(3-fluorobenzy...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474200(US10912773, Example 80 | 6-methyl-3-(tetrahydro-2H...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474210(US10912773, Example 90 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474119(US10912773, Example 12 | 7-(Cycloheptylmethyl)-3- ...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474162(US10912773, Example 44 | 6-ethyl-7-(4-methoxybenzy...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474167(US10912773, Example 50 | 7-(benzo[d][1,3]dioxol-5-...)
Affinity DataIC50: 16nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474131(US10912773, Example 24 | 7-(4-Fluorobenzyl)-6-meth...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474172(US10912773, Example 55-isomer-1 | 7-(4-methoxybenz...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474182(US10912773, Example 63 | 7-(cyclopentylmethyl)-6-m...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474190(US10912773, Example 70 | 7-(4-methoxybenzyl)-6-met...)
Affinity DataIC50: 17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM474121(US10912773, Example 14 | 7-(4-Chlorobenzyl)-6-meth...)
Affinity DataIC50: 18nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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