Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 9621
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474482(2-(2,6-Dichloro-phenyl)-5- (4-methanesulfonyl- phe...)
Affinity DataIC50: 2.30nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474483(2-(2-Chloro-6-fluoro- phenyl)-5-(4- methanesulfony...)
Affinity DataIC50: 2.70nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474463(Example Q-26 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 5.30nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474478(Example U-16 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 7.5nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474479(Example U-17 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 8.40nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474465(Example Q-20 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 9.20nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474477(Example U-12 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 9.60nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474467(Example Q-54 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 9.80nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474476(Example U-7 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 11.2nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474470(Example Q-53 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 12.9nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474456(Example Q-3 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 13.5nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474480(Example U-21 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 13.7nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474464(Example Q-27 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 13.8nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474481(Example U-18 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 13.8nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474462(Example Q-25 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 14.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474474(Example U-4 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 15.1nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474473(Example U-3 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 20.5nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474482(2-(2,6-Dichloro-phenyl)-5- (4-methanesulfonyl- phe...)
Affinity DataIC50: 21.9nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474472(Example U-2 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 22.7nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474475(Example U-6 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 23.4nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474466(Example Q-51 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 25nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474483(2-(2-Chloro-6-fluoro- phenyl)-5-(4- methanesulfony...)
Affinity DataIC50: 28.7nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474477(Example U-12 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 36nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474478(Example U-16 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 41.1nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474463(Example Q-26 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 47.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474479(Example U-17 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 58.1nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474464(Example Q-27 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 65.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474477(Example U-12 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 67.2nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sareum

US Patent
LigandPNGBDBM474484(5-(4-Methanesulfonyl- phenylamino)-2-(2,4,6- trifl...)
Affinity DataIC50: 68.3nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474483(2-(2-Chloro-6-fluoro- phenyl)-5-(4- methanesulfony...)
Affinity DataIC50: 72.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474472(Example U-2 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 75.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474462(Example Q-25 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 78.2nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474482(2-(2,6-Dichloro-phenyl)-5- (4-methanesulfonyl- phe...)
Affinity DataIC50: 87.7nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474465(Example Q-20 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 88.6nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474456(Example Q-3 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 90.2nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474463(Example Q-26 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 95nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandPNGBDBM474480(Example U-21 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 99.2nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474478(Example U-16 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 101nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474464(Example Q-27 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 109nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474465(Example Q-20 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 112nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474481(Example U-18 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 118nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474479(Example U-17 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 119nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474476(Example U-7 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 123nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandPNGBDBM474477(Example U-12 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 126nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474462(Example Q-25 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 147nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474480(Example U-21 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 153nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandPNGBDBM474483(2-(2-Chloro-6-fluoro- phenyl)-5-(4- methanesulfony...)
Affinity DataIC50: 165nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Sareum

US Patent
LigandPNGBDBM474481(Example U-18 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 165nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Sareum

US Patent
LigandPNGBDBM474480(Example U-21 in WO2008/139161 | US10882829, Exampl...)
Affinity DataIC50: 167nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Sareum

US Patent
LigandPNGBDBM474475(Example U-6 in WO2008/139161 | US10882829, Example...)
Affinity DataIC50: 169nMAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure: 1) Prepare indicated substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2021
Entry Details
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