Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 9601
LigandPNGBDBM476554(US10875854, Example 27)
Affinity DataEC50:  37.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476546(US10875854, Example 19 | 3-Methoxy-4-(3-methyl-1,2...)
Affinity DataEC50:  26.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476547(US10875854, Example 20 | 5-Amino-2-(4-methylimidaz...)
Affinity DataEC50:  49.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476548(US10875854, Example 21 | 3-methoxy-4-(2-methyl-4-p...)
Affinity DataEC50:  21.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476549(US10875854, Example 22 | 2-[2-[[(8 endo)-3-(6-meth...)
Affinity DataEC50:  34.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476550(US10875854, Example 23)
Affinity DataEC50:  40nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476551(US10875854, Example 33 | US10875854, Example 24)
Affinity DataEC50:  39nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476552(US10875854, Example 25 | 4-(4-chloroimidazol-1-yl)...)
Affinity DataEC50:  27nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476553(US10875854, Example 26 | 4-(3-chloro-1,2,4-triazol...)
Affinity DataEC50:  42.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476545(US10875854, Example 18 | (8-endo)-3-(3-methyl-1,2,...)
Affinity DataEC50:  37.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476555(US10875854, Example 28 | 8-isopropyl-N-((8 endo)-3...)
Affinity DataEC50:  19.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476556(US10875854, Example 29)
Affinity DataEC50:  14.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476557(US10875854, Example 30)
Affinity DataEC50:  13.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476558(US10875854, Example 31)
Affinity DataEC50:  49nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476559(US10875854, Example 32 | (8 endo)-3-(5-methyl-1,3,...)
Affinity DataEC50:  43.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476551(US10875854, Example 33 | US10875854, Example 24)
Affinity DataEC50:  39nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476561(US10875854, Example 34 | N-[3-methoxy-4-(3-methyl-...)
Affinity DataEC50:  40.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476562(US10875854, Example 35 | N-[4-(4-chloroimidazol-1-...)
Affinity DataEC50:  31.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476537(US10875854, Example 10 | 2-(2-((3-(difluoromethoxy...)
Affinity DataEC50:  45.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476529(N-((8 endo)-3-(3-methylisothiazol-5-yl)-3-azabicyc...)
Affinity DataEC50:  7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476530(8-methyl-5-(2,2,2-trifluoroethoxy)-N-((8 endo)-3-(...)
Affinity DataEC50:  20.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476531(8-methyl-N-((8 endo)-3-(6-methylpyrimidin-4-yl)-3-...)
Affinity DataEC50:  29.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476532(N-((8 endo)-3-(2-chloropyridin-4-yl)-3-azabicyclo[...)
Affinity DataEC50:  9.20nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476533(US10875854, Example 6 | N-((8 endo)-3-(2-methoxypy...)
Affinity DataEC50:  15.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476534(US10875854, Example 7 | N-((8 endo)-3-(6-chloropyr...)
Affinity DataEC50:  46.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476535(US10875854, Example 8 | 2-(5-(2,2,2-trifluoroethox...)
Affinity DataEC50:  44.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476536(US10875854, Example 9 | 2-(2-(((8 endo)-3-(6-methy...)
Affinity DataEC50:  43.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476528(5-(2,2,2-trifluoroethoxy)-N-((8 endo)-3-(2-(triflu...)
Affinity DataEC50:  43.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM476538(US10875854, Example 11 | 8-isopropyl-5-(2,2,2-trif...)
Affinity DataEC50:  33.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476539(US10875854, Example 12)
Affinity DataEC50:  38.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476540(US10875854, Example 13)
Affinity DataEC50:  11.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476541(US10875854, Example 14)
Affinity DataEC50:  25.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476542(US10875854, Example 15)
Affinity DataEC50:  23.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476543(US10875854, Example 16)
Affinity DataEC50:  34.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent

LigandPNGBDBM476544(US10875854, Example 17 | (8 endo)-3-(6-methoxypyri...)
Affinity DataEC50:  21.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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US Patent