Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 9598
TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM246868({1-{1-[3-Fluoro-2- (trifluoromethyl) isonicotinoyl...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
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TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50: 0.430nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
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TargetTyrosine-protein kinase JAK1(Human)
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US Patent
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)
Affinity DataIC50: 0.630nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.35nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM147798(US8962608, 28-117 | US10875847, Reference Compound...)
Affinity DataIC50: 1.67nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM185700(US9271981, 1a | US9161939, 1a | US10875847, Compou...)
Affinity DataIC50: 3.40nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50: 5.89nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
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LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 17.7nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
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US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 216nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50: 1.13E+3nMMore data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
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US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: 1.25E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
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