Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 9560
TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474372(US10858366, Example 61 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  2.30E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474374(US10858366, Example 64 | (S)-6-benzhydryl-3-((dime...)
Affinity DataEC50:  2.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474374(US10858366, Example 64 | (S)-6-benzhydryl-3-((dime...)
Affinity DataEC50:  4.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474374(US10858366, Example 64 | (S)-6-benzhydryl-3-((dime...)
Affinity DataEC50:  1.70E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474373(US10858366, Example 63 | (S)-6-benzhydryl-3- ((cyc...)
Affinity DataEC50:  3.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474373(US10858366, Example 63 | (S)-6-benzhydryl-3- ((cyc...)
Affinity DataEC50:  6.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474373(US10858366, Example 63 | (S)-6-benzhydryl-3- ((cyc...)
Affinity DataEC50:  3.20E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474372(US10858366, Example 61 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474372(US10858366, Example 61 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  5.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474375(US10858366, Example 67 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  4.10E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474371(US10858366, Example 59 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474371(US10858366, Example 59 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  5.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474371(US10858366, Example 59 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.40E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474370(US10858366, Example 58 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  820nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474370(US10858366, Example 58 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474370(US10858366, Example 58 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  200nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474369(US10858366, Example 54 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474369(US10858366, Example 54 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  4.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474378(US10858366, Example 71 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.90E+4nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474380(US10858366, Example 82 | 5-benzhydryl-10-hydroxy-3...)
Affinity DataEC50:  1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474380(US10858366, Example 82 | 5-benzhydryl-10-hydroxy-3...)
Affinity DataEC50:  4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474380(US10858366, Example 82 | 5-benzhydryl-10-hydroxy-3...)
Affinity DataEC50:  1.00E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474379(US10858366, Example 79 | 6-benzhydryl-11-hydroxy-6...)
Affinity DataEC50:  390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474379(US10858366, Example 79 | 6-benzhydryl-11-hydroxy-6...)
Affinity DataEC50:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474379(US10858366, Example 79 | 6-benzhydryl-11-hydroxy-6...)
Affinity DataEC50:  610nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474378(US10858366, Example 71 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  2.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474378(US10858366, Example 71 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474369(US10858366, Example 54 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  2.60E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474377(US10858366, Example 69 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474377(US10858366, Example 69 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474377(US10858366, Example 69 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.50E+4nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474376(US10858366, Example 68 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.70E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474376(US10858366, Example 68 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  3.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474376(US10858366, Example 68 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  6.30E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474375(US10858366, Example 67 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  3.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474375(US10858366, Example 67 | (S)-6-benzhydryl-11-hydro...)
Affinity DataEC50:  1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474368(US10858366, Example 47 | (S)-6-(bis(4-fluorophenyl...)
Affinity DataEC50:  560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474368(US10858366, Example 47 | (S)-6-(bis(4-fluorophenyl...)
Affinity DataEC50:  840nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474368(US10858366, Example 47 | (S)-6-(bis(4-fluorophenyl...)
Affinity DataEC50:  290nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (A/duck/Hubei/W1/2004(H9N2)))
Novartis

US Patent
LigandPNGBDBM474367(US10858366, Example 30 | (S)-6-((S)-(3-bromophenyl...)
Affinity DataEC50:  65nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474367(US10858366, Example 30 | (S)-6-((S)-(3-bromophenyl...)
Affinity DataEC50:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474367(US10858366, Example 30 | (S)-6-((S)-(3-bromophenyl...)
Affinity DataEC50:  45nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474361(US10858366, Example 52 | (S)-6-benzhydryl-11-hydro...)
Affinity DataIC50: 8nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474346(US10858366, Example 7 | (S)-6-benzhydryl-3-bromo-1...)
Affinity DataIC50: 9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474354(US10858366, Example 24 | (S)-6-((S)-(3-fluoropheny...)
Affinity DataIC50: 9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474343(US10858366, Example 4 | (S)-6-Benzhydryl-11-hydrox...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474357(US10858366, Example 39 | (S)-6-((R)-(2-bromo-4-flu...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474367(US10858366, Example 30 | (S)-6-((S)-(3-bromophenyl...)
Affinity DataIC50: 10nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474350(US10858366, Example 18 | (S)-6-((S)-(4-fluoropheny...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolymerase acidic protein(Influenza A virus (strain A/Victoria/3/1975 H3N2))
Novartis

US Patent
LigandPNGBDBM474344(US10858366, Example 5 | (S)-6-Benzhydryl-3-chloro-...)
Affinity DataIC50: 20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

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