Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 9547
TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473766(US10844077, Compound I-9)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473746(US10844077, Compound I-3)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473764(US10844077, Compound II-2)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473751(US10844077, Compound I-8)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473751(US10844077, Compound I-8)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473750(US10844077, Compound I-7)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473750(US10844077, Compound I-7)
Affinity DataIC50: 0.495nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473766(US10844077, Compound I-9)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473701(US10844077, Compound I-1)
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473749(US10844077, Compound I-4)
Affinity DataIC50: 0.590nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473746(US10844077, Compound I-3)
Affinity DataIC50: 0.600nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473748(US10844077, Compound I-2)
Affinity DataIC50: 0.730nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473763(US10844077, Compound II-1)
Affinity DataIC50: 1.10nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473749(US10844077, Compound I-4)
Affinity DataIC50: 1.38nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473701(US10844077, Compound I-1)
Affinity DataIC50: 1.61nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473748(US10844077, Compound I-2)
Affinity DataIC50: 1.63nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473763(US10844077, Compound II-1)
Affinity DataIC50: 1.64nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473752(US10844077, Compound I-10)
Affinity DataIC50: 1.74nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)
Affinity DataIC50: 1.90nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473764(US10844077, Compound II-2)
Affinity DataIC50: 1.94nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473752(US10844077, Compound I-10)
Affinity DataIC50: 2.42nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473753(US10844077, Compound I-11)
Affinity DataIC50: 3.99nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473747(US10844077, Compound I-6)
Affinity DataIC50: 4.24nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473753(US10844077, Compound I-11)
Affinity DataIC50: 5.52nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473758(US10844077, Compound III-5)
Affinity DataIC50: 9.06nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473756(US10844077, Compound III-3)
Affinity DataIC50: 19.4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473765(US10844077, Compound II-3)
Affinity DataIC50: 19.9nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473765(US10844077, Compound II-3)
Affinity DataIC50: 25.3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473754(US10844077, Compound III-1)
Affinity DataIC50: 86.6nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473755(US10844077, Compound III-2)
Affinity DataIC50: 281nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473757(US10844077, Compound III-4)
Affinity DataIC50: 367nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473755(US10844077, Compound III-2)
Affinity DataIC50: 402nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473757(US10844077, Compound III-4)
Affinity DataIC50: 1.15E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473754(US10844077, Compound III-1)
Affinity DataIC50: 1.82E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473758(US10844077, Compound III-5)
Affinity DataIC50: 1.91E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473756(US10844077, Compound III-3)
Affinity DataIC50: 2.15E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473759(US10844077, Compound III-6)
Affinity DataIC50: 2.58E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473762(US10844077, Compound III-9)
Affinity DataIC50: 2.66E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473759(US10844077, Compound III-6)
Affinity DataIC50: 4.55E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473762(US10844077, Compound III-9)
Affinity DataIC50: 7.20E+3nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473761(US10844077, Compound III-8)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473761(US10844077, Compound III-8)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473760(US10844077, Compound III-7)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM473760(US10844077, Compound III-7)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibitory activities of exemplary compounds described herein against select protein kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent