Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 9538
TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473090(US10842803, Structure TABLE 1.20 | 6-(1H-indazol-6...)
Affinity DataIC50: 2.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473114(US10842803, Structure TABLE 1.44 | 2-hydroxy-1-(4-...)
Affinity DataIC50: 2.60E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473125(US10842803, Structure TABLE 1.55 | 1-(2-(6-(1H-pyr...)
Affinity DataIC50: 2.80E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473118(US10842803, Structure TABLE 1.48 | N-{5-methanesul...)
Affinity DataIC50: 3.70E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473072(US10842803, Structure TABLE 1.2 | N-[6-(1H-indazol...)
Affinity DataIC50: 3.80E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473108(US10842803, Structure TABLE 1.38 | 1-(4-{6-[(6-{1H...)
Affinity DataIC50: 4.29E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473102(US10842803, Structure TABLE 1.32 | N-{4H,6H,7H- py...)
Affinity DataIC50: 4.50E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473095(US10842803, Structure TABLE 1.25 | 1-(6-{[6-(1H-in...)
Affinity DataIC50: 5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473092(US10842803, Structure TABLE 1.22 | N-[6-(1H-indazo...)
Affinity DataIC50: 5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473100(US10842803, Structure TABLE 1.30 | [(2R)-4-(6-{[6-...)
Affinity DataIC50: 5.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473088(US10842803, Structure TABLE 1.18 | 1-(6-{[6-(1H-in...)
Affinity DataIC50: 6.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473078(US10842803, Structure TABLE 1.8 | N-[6-(1H-indazol...)
Affinity DataIC50: 6.20E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473082(US10842803, Structure TABLE 1.12 | N-[6-(1H-indazo...)
Affinity DataIC50: 6.60E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473127(US10842803, Structure TABLE 1.57 | 2-(6-(8-(6,7-di...)
Affinity DataIC50: 7.10E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473123(US10842803, Structure TABLE 1.53 | N-(5-methyl-6-(...)
Affinity DataIC50: 7.70E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473098(US10842803, Structure TABLE 1.28 | [(2S)-4-(6-{[6-...)
Affinity DataIC50: 8.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473097(US10842803, Structure TABLE 1.27 | 1-[(6-{[6-(1H-i...)
Affinity DataIC50: 8.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473107(US10842803, Structure TABLE 1.37 | 2-[ethyl({6-[(6...)
Affinity DataIC50: 8.50E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473089(US10842803, Structure TABLE 1.19 | 2-[(6-{[6-(1H-i...)
Affinity DataIC50: 9.00E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473117(US10842803, Structure TABLE 1.47 | 6-[8-({5- metha...)
Affinity DataIC50: 1.00E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473105(US10842803, Structure TABLE 1.35 | 1,5-dimethyl-N-...)
Affinity DataIC50: 1.05E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473124(US10842803, Structure TABLE 1.54 | 6-(8-(6,7-dihyd...)
Affinity DataIC50: 1.08E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473122(US10842803, Structure TABLE 1.52 | N-(5-(methoxyme...)
Affinity DataIC50: 1.09E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473120(US10842803, Structure TABLE 1.50 | 5-(4-ethylpiper...)
Affinity DataIC50: 1.13E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473162(US10842803, Structure TABLE 1.92 | 5-(5-chloro-8-(...)
Affinity DataIC50: 1.20E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473131(US10842803, Structure TABLE 1.61 | N-(6-(1H-indazo...)
Affinity DataIC50: 1.28E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473134(US10842803, Structure TABLE 1.64 | N-(6-(1H-indol-...)
Affinity DataIC50: 1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473091(US10842803, Structure TABLE 1.21 | 2-N-[6-(1H-inda...)
Affinity DataIC50: 1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473112(US10842803, Structure TABLE 1.42 | 6-(8-{[5- (hydr...)
Affinity DataIC50: 1.30E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473076(US10842803, Structure TABLE 1.6 | 6-{8-[(5,6- dime...)
Affinity DataIC50: 1.33E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473158(US10842803, Structure TABLE 1.88 | 5-chloro-N-(5-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473094(US10842803, Structure TABLE 1.24 | 6-(8-{[6-(morph...)
Affinity DataIC50: 1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473099(US10842803, Structure TABLE 1.29 | N-[6-(1H-indazo...)
Affinity DataIC50: 1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473161(US10842803, Structure TABLE 1.91 | 2-(6-(5-chloro-...)
Affinity DataIC50: 1.50E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473119(US10842803, Structure TABLE 1.49 | 6-(8-{[5-(4- ac...)
Affinity DataIC50: 1.55E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473138(US10842803, Structure TABLE 1.68 | 2-(6-(8-(5- mor...)
Affinity DataIC50: 1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473139(US10842803, Structure TABLE 1.69 | N-(5-(4-ethylpi...)
Affinity DataIC50: 1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473159(US10842803, Structure TABLE 1.89 | 6-(5-chloro-8-(...)
Affinity DataIC50: 1.70E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473113(US10842803, Structure TABLE 1.43 | 6-[8-({5-acetyl...)
Affinity DataIC50: 1.80E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473074(US10842803, Structure TABLE 1.4 | N-[6-(1,3-benzot...)
Affinity DataIC50: 1.82E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473136(US10842803, Structure TABLE 1.66 | 6-(8-(5-(1-hydr...)
Affinity DataIC50: 1.90E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473128(US10842803, Structure TABLE 1.58 | 5-(8-(5-(2- hyd...)
Affinity DataIC50: 1.97E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473096(US10842803, Structure TABLE 1.26 | 1-(6-{[6-(1H-in...)
Affinity DataIC50: 2.00E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473116(US10842803, Structure TABLE 1.46 | {1-methyl-3-[(6...)
Affinity DataIC50: 2.08E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473135(US10842803, Structure TABLE 1.65 | N-(5-cyclopropy...)
Affinity DataIC50: 2.20E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473075(US10842803, Structure TABLE 1.5 | 7-{8-[(5,6- dime...)
Affinity DataIC50: 2.24E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473087(US10842803, Structure TABLE 1.17 | 2-N-[6-(1H-inda...)
Affinity DataIC50: 2.31E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473103(US10842803, Structure TABLE 1.33 | 1-methyl-N-(6-{...)
Affinity DataIC50: 2.32E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473077(US10842803, Structure TABLE 1.7 | N-[6-(3,4-dihydr...)
Affinity DataIC50: 2.37E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Kronos Bio

US Patent
LigandPNGBDBM473121(US10842803, Structure TABLE 1.51 | 2-(6-(8-(5- mor...)
Affinity DataIC50: 2.39E+4nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2021
Entry Details
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