Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 9397
TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM463759(2-[(3R)-1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-...)
Affinity DataIC50: 9nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM463759(2-[(3R)-1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-...)
Affinity DataIC50: 19nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM463760(2-[1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-4-(tr...)
Affinity DataIC50: 27nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM463760(2-[1-[5-cyano-6-[(2S)-2-methylazetidin-1-yl]-4-(tr...)
Affinity DataIC50: 37nMAssay Description:The intrinsic potency of the compounds may be measured using an enzymatic assay which measures the production of F P. Compounds are prepared in DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
Go to US Patent