Compile Data Set for Download or QSAR
Report error Found 424 Enz. Inhib. hit(s) with all data for entry = 9331
TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352621(US9809561, 37J | (R)-tert-butyl (2-(2- (oxazolidin...)
Affinity DataIC50: 1.96nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352910(US9809561, 115B | US10745364, Example 115A)
Affinity DataIC50: 2.03nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352646(US9809561, 37AH | (S)-neopentyl (2-(2- (methylamin...)
Affinity DataIC50: 2.11nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352591(US9809561, 30C | (S)-methyl 2-(6-((tert- butoxycar...)
Affinity DataIC50: 2.15nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352589(US9809561, 30A | (S)-methyl 2-(6-((tert- butoxycar...)
Affinity DataIC50: 2.24nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352725(US9809561, 49 | tert-butyl (2-(cyanomethyl)-4-((3-...)
Affinity DataIC50: 2.46nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352638(US9809561, 37AA | (S)-methyl 3-(2-(6-((tert- butox...)
Affinity DataIC50: 2.53nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352645(US9809561, 37AG | (S)-tert-butyl (2-(2- (oxazolidi...)
Affinity DataIC50: 2.56nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352512((S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((4-flu...)
Affinity DataIC50: 2.72nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352785(US9809561, 63F | (S)-tert-butyl (2-((2H-1,2,3-tria...)
Affinity DataIC50: 2.78nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352784(US9809561, 63E | (S)-tert-butyl (2-((1H-1,2,3-tria...)
Affinity DataIC50: 2.80nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352619(US9809561, 37H | (S)-tert-butyl (4-((3-chloro-4- ...)
Affinity DataIC50: 2.81nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352481((R)-tert-butyl (2-(hydroxymethyl)-4-((3-(trifluoro...)
Affinity DataIC50: 3.01nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352537(US9809561, 13Y | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 3.04nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352782(US9809561, 63C | (S)-tert-butyl (2-((1H-1,2,4-tria...)
Affinity DataIC50: 3.04nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352849(US9809561, 92 | US10745364, Example 92)
Affinity DataIC50: 3.11nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352590(US9809561, 30B | (S)-methyl 2-(6-((tert- butoxycar...)
Affinity DataIC50: 3.13nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352748(US9809561, 55A | (S)-tert-butyl (2-(2-acetamido-2-...)
Affinity DataIC50: 3.13nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352552(US9809561, 16 | US9809561, 18 | (R)-tert-butyl (2-...)
Affinity DataIC50: 3.28nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352821(US9809561, 81F | 1,1,1-trifluoro-2-methylpropan-2-...)
Affinity DataIC50: 3.33nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352744(US9809561, 53P | (R)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 3.42nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352908(US9809561, 114D | 2,2,2-trifluoro-1,1- dimethyleth...)
Affinity DataIC50: 3.46nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352746(US9809561, 54 | (S)-tert-butyl (2-(2-acetamido-2-m...)
Affinity DataIC50: 3.49nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352775(US9809561, 58 | tert-butyl (2-(2-hydroxyethyl)-4-(...)
Affinity DataIC50: 3.56nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352613(US9809561, 37B | (S)-tert-butyl (2-(2- amino-2-oxo...)
Affinity DataIC50: 3.66nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352588(US9809561, 29 | (S)-methyl 2-(6-((tert-butoxycarbo...)
Affinity DataIC50: 3.76nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352629(US9809561, 37R | (S)-tert-butyl (2-(2- oxo-2-((pyr...)
Affinity DataIC50: 3.79nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352558(US9809561, 17F | (R)-tert-butyl (2- ((methylsulfon...)
Affinity DataIC50: 3.86nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352905(2,2,2-trifluoro-1,1- dimethylethyl {l-[(3- chloro-...)
Affinity DataIC50: 3.87nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352612(US9809561, 37A | (S)-tert-butyl (2-(2- amino-2-oxo...)
Affinity DataIC50: 3.89nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352540(US9809561, 13AB | (S)-1,1,1-trifluoro-2-methylprop...)
Affinity DataIC50: 3.92nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352544(US9809561, 13AF | (S)-1,1,1-trifluoro-2-methylprop...)
Affinity DataIC50: 3.93nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352755(US9809561, 57B | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 3.99nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352700(US9809561, 44 | (S)-(2-(2-(methoxyamino)-2-oxoethy...)
Affinity DataIC50: 4.07nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352729(US9809561, 53A | (S)-tert-butyl (2-(2-propionamido...)
Affinity DataIC50: 4.07nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352752(US9809561, 55E | (R)-tert-butyl (2-(2-acetamido-2-...)
Affinity DataIC50: 4.09nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352545(US9809561, 14 | (R)-tert-butyl (2-((pyridin-2-ylth...)
Affinity DataIC50: 4.13nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352552(US9809561, 16 | US9809561, 18 | (R)-tert-butyl (2-...)
Affinity DataIC50: 4.16nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352644(US9809561, 37AF | (S)-tert-butyl (2-(2-(ethylamin...)
Affinity DataIC50: 4.16nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352758(US9809561, 57E | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 4.17nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352906(US9809561, 114B | 2,2,2-trifluoro-1,1- dimethyleth...)
Affinity DataIC50: 4.19nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352499(US9809561, 9 | US10745364, Example 9)
Affinity DataIC50: 4.23nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352643(US9809561, 37AE | (S)-tert-butyl (2-(2-oxo-2- (pr...)
Affinity DataIC50: 4.38nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352733(US9809561, 53E | (S)-tert-butyl (2-(2-acetamidoeth...)
Affinity DataIC50: 4.38nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352630(US9809561, 37S | (S)-tert-butyl (2- (2-(((1-ethyl-...)
Affinity DataIC50: 4.47nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352918(US9809561, 119 | US10745364, Example 119)
Affinity DataIC50: 4.49nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352757(US9809561, 57D | (S)-1,1,1-trifluoro-2-methylpropa...)
Affinity DataIC50: 4.52nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352859(US9809561, 95E | (S)-1,1,1-trifluoro-2- methylprop...)
Affinity DataIC50: 4.52nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352484([(R)-4-(3-chloro-benzenesulfonyl)-2- hydroxymethyl...)
Affinity DataIC50: 4.57nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Lycera

US Patent
LigandPNGBDBM352789(US9809561, 65 | tert-butyl (2-(2-hydroxy-2-methyl...)
Affinity DataIC50: 4.57nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
Go to US Patent

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