Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 9264
TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453713(2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-1-(...)
Affinity DataIC50: 1.5nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453711(2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-4-f...)
Affinity DataIC50: 1.90nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453704(2-(9-Ethyl-6-fluoro-8-methyl-9H-carbazol-3-yl)-1-(...)
Affinity DataIC50: 2nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453702(2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-1-(...)
Affinity DataIC50: 2.40nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453710(2-(9-Ethyl-6-fluoro-8-methyl-9H-carbazol-3-yl)-4-f...)
Affinity DataIC50: 2.40nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453715(2-(8-Chloro-9-ethyl-6-methyl-9H-carbazol-3-yl)-1-(...)
Affinity DataIC50: 2.80nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453700(2-(6-Bromo-9-ethyl-9H-carbazol-3-yl)-1-(2-methoxye...)
Affinity DataIC50: 11nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453718(2-(5-Chloro-9-ethyl-6-methyl-9H-carbazol-3-yl)-1-(...)
Affinity DataIC50: 23nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453699(Methyl 2-(6-bromo-9-ethyl-9H-carbazol-3-yl)-1-(2-m...)
Affinity DataIC50: 32nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453701(Methyl 2-(9-ethyl-8-fluoro-6-methyl-9H-carbazol-3-...)
Affinity DataIC50: 40nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453714(Methyl 2-(8-chloro-9-ethyl-6-methyl-9H-carbazol-3-...)
Affinity DataIC50: 47nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453712(Ethyl 2-(9-ethyl-8-fluoro-6-methyl-9H-carbazol-3-y...)
Affinity DataIC50: 62nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent