Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 9261
TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453543(US10730849, Example 8)
Affinity DataEC50:  1.55E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453555(US10730849, Example 20)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453554(US10730849, Example 19)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453553(US10730849, Example 18)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453552(US10730849, Example 17)
Affinity DataEC50:  1.48E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453551(4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...)
Affinity DataEC50:  2.48E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453550((S)-4-(6-bromo-5- methoxybenzo[b]thiophen-2-yl)-2-...)
Affinity DataEC50:  894nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453549(US10730849, Example 14 | US10730849, Example 25 | ...)
Affinity DataEC50:  8.64E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453548(US10730849, Example 13 | (S)-4-(4-fluoro-5,6- dime...)
Affinity DataEC50:  2.08E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453546(US10730849, Example 11)
Affinity DataEC50:  3.87E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453545(US10730849, Example 10)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453544(US10730849, Example 9)
Affinity DataEC50:  1.09E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453556(US10730849, Example 21)
Affinity DataEC50:  1.43E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453542(US10730849, Example 7)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453539(US10730849, Example 4)
Affinity DataEC50:  1.15E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453538(US10730849, Example 3)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453537(US10730849, Example 2)
Affinity DataEC50:  1.12E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453536(US10730849, Example 1)
Affinity DataEC50:  5.17E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453589(US10730849, Example 54)
Affinity DataEC50:  531nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453588(US10730849, Example 53)
Affinity DataEC50:  1.37E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453586(US10730849, Example 51 | (1R,2S)-2-(4-fluoro-5,6-d...)
Affinity DataEC50:  599nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453586(US10730849, Example 51 | (1R,2S)-2-(4-fluoro-5,6-d...)
Affinity DataEC50:  1.78E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453585(US10730849, Example 50)
Affinity DataEC50:  890nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453584(US10730849, Example 49)
Affinity DataEC50:  2.72E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453568((S)-4-(5-chloro-6- ethoxybenzo[b] thiophen- 2-yl)-...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453588(US10730849, Example 53)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453586(US10730849, Example 51 | (1R,2S)-2-(4-fluoro-5,6-d...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453586(US10730849, Example 51 | (1R,2S)-2-(4-fluoro-5,6-d...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453585(US10730849, Example 50)
Affinity DataEC50:  2.14E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453583(US10730849, Example 48)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453581((2S)-4-[6-(2-fluoroethyl)-5-methoxy-1- benzothioph...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453578(US10730849, Example 43)
Affinity DataEC50:  4.11E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453576(US10730849, Example 41)
Affinity DataEC50:  1.47E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453571(US10730849, Example 36)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453570(US10730849, Example 35)
Affinity DataEC50:  7.67E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453569((S)-4-(5-bromo- 6-methylbenzo[b] thiophen-2-yl)-2-...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453583(US10730849, Example 48)
Affinity DataEC50:  1.93E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453567((S)-4-(6-bromo-5- chlorobenzo[b]thiophen- 2-yl)-2-...)
Affinity DataEC50:  1.70E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453566((S)-4-(5,6-dimethylbenzo [b]thiophen-2-y1)- 2-meth...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453565((S)-4-(5-fluoro-6- methoxybenzo[b] thiophen- 2-yl)...)
Affinity DataEC50:  1.87E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453564((S)-4-(6-bromo-5- methylbenzo[b] thiophen-2-yl)- 2...)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453563(US10730849, Example 28)
Affinity DataEC50:  9.26E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453562(US10730849, Example 27)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453548(US10730849, Example 13 | (S)-4-(4-fluoro-5,6- dime...)
Affinity DataEC50:  2.08E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453549(US10730849, Example 14 | US10730849, Example 25 | ...)
Affinity DataEC50:  8.64E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453559(US10730849, Example 24)
Affinity DataEC50:  8.54E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453558(US10730849, Example 23)
Affinity DataEC50:  2.00E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453557(US10730849, Example 22)
Affinity DataEC50:  1.71E+4nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453548(US10730849, Example 13 | (S)-4-(4-fluoro-5,6- dime...)
Affinity DataEC50:  1.38E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM453559(US10730849, Example 24)
Affinity DataEC50:  2.64E+3nMAssay Description:The individual compounds described in the Examples herein are defined as STING agonists by (i) binding to the STING protein as evidenced by a reducti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

Displayed 1 to 50 (of 95 total ) | Next | Last >>
Jump to: