Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 9105
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441970(US10647700, Compound 24)
Affinity DataIC50: 16nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441969(US10647700, Compound 23)
Affinity DataIC50: 20nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441971(US10647700, Compound 25)
Affinity DataIC50: 23nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441968(US10647700, Compound 22)
Affinity DataIC50: 29nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441962(US10647700, Compound 16)
Affinity DataIC50: 58.6nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441960(US10647700, Compound 14)
Affinity DataIC50: 75nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441961(US10647700, Compound 15)
Affinity DataIC50: 80.6nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441966(US10647700, Compound 20)
Affinity DataIC50: 103nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441967(US10647700, Compound 21)
Affinity DataIC50: 103nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM50017293(CHEMBL3287735 | US10647700, Compound GSK126)
Affinity DataIC50: 121nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
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TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM172038(US10647700, Compound EPZ6438 | BDBM190183 | US1015...)
Affinity DataIC50: 219nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441965(US10647700, Compound 19)
Affinity DataIC50: 220nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441963(US10647700, Compound 17)
Affinity DataIC50: 444nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Tarapeutics Science

US Patent
LigandPNGBDBM441964(US10647700, Compound 18)
Affinity DataIC50: 515nMAssay Description:Enzymatic activity assay was conducted using EZH2(Y641F) TR-FRET assay KIT from Cisbio company on compounds that were shown to be active in primary s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
Go to US Patent