Compile Data Set for Download or QSAR
Report error Found 212 Enz. Inhib. hit(s) with all data for entry = 9024
TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436039(US10611730, Example 211 | 6-(2-Chloro-6-(trifluoro...)
Affinity DataIC50: 0.100nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50459021(CHEMBL4212408 | US10611730, Example 76)
Affinity DataIC50: 2.51nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436042(US10611730, Example 214 | 6-(2-Chloro-6-(trifluoro...)
Affinity DataIC50: 2.51nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435960(US10611730, Example 133 | 2-[3-Chloro-2-(2-oxo-3H-...)
Affinity DataIC50: 3.16nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435917(US10611730, Example 89 | 5-[2-(Cyclopropylmethoxy)...)
Affinity DataIC50: 3.98nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50459026(CHEMBL4214902 | US10611730, Example 31)
Affinity DataIC50: 6.31nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50459028(CHEMBL4216045 | US10611730, Example 160)
Affinity DataIC50: 6.31nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436013(US10611730, Example 186 | tert-Butyl 5-[2-chloro-3...)
Affinity DataIC50: 6.31nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435916(US10611730, Example 88 | 5-[2-Isopropoxy-6-(triflu...)
Affinity DataIC50: 7.94nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435950(2-[3,4-Dichloro-2-(2-oxo-1,3-dihydrobenzimidazol-5...)
Affinity DataIC50: 7.94nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435894(US10611730, Example 66 | 5-(2,3,6-Trichlorophenyl)...)
Affinity DataIC50: 10nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435920(US10611730, Example 92 | 5-[2-Chloro-6-(cyclopropy...)
Affinity DataIC50: 10nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436029(US10611730, Example 201 | 5-(3-(3-Cyclopropyl-1,2,...)
Affinity DataIC50: 10nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435905(US10611730, Example 77 | 6-(2-Isopropoxy-6-methoxy...)
Affinity DataIC50: 12.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50459030(CHEMBL4207238 | US10611730, Example 124)
Affinity DataIC50: 12.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435953((+-)-2-[3-Chloro-2-(2-oxo-1,3-dihydrobenzimidazol-...)
Affinity DataIC50: 12.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436015(US10611730, Example 188 | 5-[2-Chloro-3-(1-piperid...)
Affinity DataIC50: 12.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435765(5-(2,6-Dichloro-3-methyl-phenyl)-1,3-dihydrobenzim...)
Affinity DataIC50: 15.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435951(2-[2-(2-Oxo-1,3-dihydrobenzimidazol-5-yl)-3-triflu...)
Affinity DataIC50: 15.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436036(US10611730, Example 208 | 2-Chloro-3-(2-oxo-1,3-di...)
Affinity DataIC50: 15.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436037(US10611730, Example 209 | 4-Chloro-3-(2-oxo-1,3-di...)
Affinity DataIC50: 15.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435903(US10611730, Example 75 | 5-[2-Methyl-3-[5-(4-pyrid...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435921(US10611730, Example 93 | (+-)-5-[2-Chloro-6-[(2,2-...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435962(US10611730, Example 135 | 2-[3-(4-Fluorophenyl)-2-...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435976(US10611730, Example 149 | 5-[3-[(2,2-Dimethylmorph...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435989(US10611730, Example 162 | 5-(2-Chloro-6-phenyl-phe...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435990(US10611730, Example 163 | 5-[2-Chloro-6-(4-fluorop...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436026(US10611730, Example 198 | 5-[2-Methyl-3-[5-(triflu...)
Affinity DataIC50: 20nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435954(2-[3-Chloro-2-(2-oxo-1,3-dihydrobenzimidazol-5-yl)...)
Affinity DataIC50: 25.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435756(5-(2-Isobutoxy-6-methoxy-phenyl)-1,3-dihydrobenzim...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435757(5-(2-Isobutoxy-5-methyl-phenyl)-1,3-dihydrobenzimi...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435772(5-[3-Chloro-2-(trifluoromethoxy)phenyl]-1,3-dihydr...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435785(US10611730, Example 43 | Methyl 2-chloro-3-(2-oxo-...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435901(US10611730, Example 73 | 5-[3-(5-Cyclopropyl-1,2,4...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435922(US10611730, Example 94 | 5-[2-Chloro-6-(difluorome...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435938(US10611730, Example 110 | 5-(2-Chloro-3-isopropoxy...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435946((+-)-5-[2-Chloro-6-(2,2,2-trifluoro-1-methyl-ethox...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435959(US10611730, Example 132 | 2-[3-Bromo-2-(2-oxo-1,3-...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435978(US10611730, Example 151 | (+-)-5-[2-Methyl-3-[[2-(...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435988(US10611730, Example 161 | 5-(2-Chloro-6-vinyl-phen...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436034(US10611730, Example 206 | 5-[2-Methyl-3-(1,2,4-oxa...)
Affinity DataIC50: 31.6nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435889(US10611730, Example 61 | 5-[2-Chloro-3-(trifluorom...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435933(US10611730, Example 105 | 5-(2-Benzyloxy-6-methoxy...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435934(US10611730, Example 106 | 5-[2-[(4-Fluorophenyl)et...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435937(US10611730, Example 109 | 5-[2-Chloro-3-(cycloprop...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435991(US10611730, Example 164 | 4-[3-Chloro-2-(2-oxo-1,3...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436031(US10611730, Example 203 | 5-[2-Methyl-3-(3-methyl-...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436033(US10611730, Example 205 | 5-[2-Methyl-3-[3-(triflu...)
Affinity DataIC50: 39.8nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435788(US10611730, Example 46 | Methyl 2-methyl-3-(2-oxo-...)
Affinity DataIC50: 50.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM435899(US10611730, Example 71 | 5-[2-Methyl-3-(5-methyl-1...)
Affinity DataIC50: 50.1nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent

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