Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8962
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432120(US10577353, Compound 15 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432133(US10577353, Compound 28 | (S)-2-(tert-butoxy)-2-(5...)
Affinity DataEC50:  13nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432132(US10577353, Compound 27 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432127(US10577353, Compound 26 | (S)-2-(5-(2-(5H-pyrrolo[...)
Affinity DataEC50:  20nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432130(US10577353, Compound 25 | (S)-2-(5-(2-(7H-pyrrolo[...)
Affinity DataEC50:  4nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432129(US10577353, Compound 24 | (S)-2-(5-(2-(1H-imidazo[...)
Affinity DataEC50:  56nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432128(US10577353, Compound 23 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  62nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432127(US10577353, Compound 26 | (S)-2-(5-(2-(5H-pyrrolo[...)
Affinity DataEC50:  286nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432126(US10577353, Compound 21 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  5.99E+3nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432125(US10577353, Compound 20 | (S)-2-(5-(2-(7H-pyrrolo[...)
Affinity DataEC50:  3nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432124(US10577353, Compound 19 | (S)-2-(tert-butoxy)-2-(5...)
Affinity DataEC50:  1nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432123(US10577353, Compound 18 | (S)-2-(5-(2-(benzo[d]iso...)
Affinity DataEC50:  5nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432122(US10577353, Compound 17 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  22nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432121(US10577353, Compound 16 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432103(US10577353, Compound 1 | (S)-2-(tert-butoxy)-2-(4-...)
Affinity DataEC50:  3nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432119(US10577353, Compound 14 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432118(US10577353, Compound 13 | (S)-2-(5-(2-(benzo[d]thi...)
Affinity DataEC50:  7nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432117(US10577353, Compound 12 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  4nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432116(US10577353, Compound 11 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  1nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432115(US10577353, Compound 10 | (S)-2-(tert-butoxy)-2-(4...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432114(US10577353, Compound 9 | (S)-2-(tert-butoxy)-2-(4-...)
Affinity DataEC50:  8nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432113(US10577353, Compound 8 | (S)-2-(tert-butoxy)-2-(4-...)
Affinity DataEC50:  5nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432112(US10577353, Compound 7 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  2nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432111(US10577353, Compound 6 | (S)-2-(tert-butoxy)-2-(4-...)
Affinity DataEC50:  22nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432108(US10577353, Compound 5 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  12nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432106(US10577353, Compound 4 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  19nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432105(US10577353, Compound 3 | (S)-2-(tert-butoxy)-2-(5-...)
Affinity DataEC50:  1nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Viiv Healthcare UK (No. 5)

US Patent
LigandPNGBDBM432104(US10577353, Compound 2 | (S)-2-(tert-butoxy)-2-(4-...)
Affinity DataEC50:  1nMAssay Description:A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent