Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8849
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-2 | US10501451, Example 2...)
Affinity DataKi:  2.79nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-2 | US10501451, Example ...)
Affinity DataKi:  2.80nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423285(US10501451, Example 11, P-2 | US10501451, Example ...)
Affinity DataKi:  3.06nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423283(US10501451, Example 10, P-2 | US10501451, Example ...)
Affinity DataKi:  3.20nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423287(US10501451, Example 12, P-2 | US10501451, Example ...)
Affinity DataKi:  3.90nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423289(US10501451, Example 13, P-2 | US10501451, Example ...)
Affinity DataKi:  4.03nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423267(US10501451, Example 1, P-2 | US10501451, Example 1...)
Affinity DataKi:  4.08nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423273(US10501451, Example 5, P-2 | US10501451, Example 5...)
Affinity DataKi:  4.37nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423277(US10501451, Example 7, P-2 | US10501451, Example 7...)
Affinity DataKi:  4.98nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423272((Racemic Mixture) | US10501451, Example 4 | US1095...)
Affinity DataKi:  5.49nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423275(US10501451, Example 6, P-2 | US10501451, Example 6...)
Affinity DataKi:  6.53nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423275(US10501451, Example 6, P-2 | US10501451, Example 6...)
Affinity DataKi:  8.16nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423283(US10501451, Example 10, P-2 | US10501451, Example ...)
Affinity DataKi:  10.7nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423281(US10501451, Example 9, P-2 | US10501451, Example 9...)
Affinity DataKi:  12.1nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423293(US10501451, Example 15, P-2 | US10501451, Example ...)
Affinity DataKi:  12.5nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423271((Racemic Mixture) | US10501451, Example 3 | US1095...)
Affinity DataKi:  15.1nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423279(US10501451, Example 8, P-2 | US10501451, Example 8...)
Affinity DataKi:  18.8nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423285(US10501451, Example 11, P-2 | US10501451, Example ...)
Affinity DataKi:  39.3nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423279(US10501451, Example 8, P-2 | US10501451, Example 8...)
Affinity DataKi:  57.8nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423291(US10501451, Example 14, P-2 | US10501451, Example ...)
Affinity DataKi:  98.7nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423269(US10501451, Example 2, P-2 | US10501451, Example 2...)
Affinity DataKi:  112nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423277(US10501451, Example 7, P-2 | US10501451, Example 7...)
Affinity DataKi:  125nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423281(US10501451, Example 9, P-2 | US10501451, Example 9...)
Affinity DataKi:  139nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423273(US10501451, Example 5, P-2 | US10501451, Example 5...)
Affinity DataKi:  144nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423287(US10501451, Example 12, P-2 | US10501451, Example ...)
Affinity DataKi:  150nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423267(US10501451, Example 1, P-2 | US10501451, Example 1...)
Affinity DataKi:  305nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423289(US10501451, Example 13, P-2 | US10501451, Example ...)
Affinity DataKi:  367nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM423293(US10501451, Example 15, P-2 | US10501451, Example ...)
Affinity DataKi:  393nMAssay Description:Binding experiments to determine binding to NR2B-subtype NMDA receptors were performed on forebrains of 8-10 weeks old male Sprague Dawley rats (Harl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
Go to US Patent