Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 8763
TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259423(US9512084, 22 | US10457647, Example 22 | US1118046...)
Affinity DataIC50: 0.100nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259427(US9512084, 26 | US10457647, Example 26 | US1118046...)
Affinity DataIC50: 0.400nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259425(US9512084, 24 | US10457647, Example 24 | US1118046...)
Affinity DataIC50: 0.5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259404(US9512084, 3 | US10457647, Example 3 | US11180460,...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259440(US9512084, 39 | US10457647, Example 39 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259407(US9512084, 6 | US10457647, Example 6 | US11180460,...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259419(US9512084, 18 | US10457647, Example 18 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259424(US9512084, 23 | US10457647, Example 23 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259434(US9512084, 33 | US10457647, Example 33 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259429(US9512084, 28 | US10457647, Example 28 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259426(US9512084, 25 | US10457647, Example 25 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259415(US9512084, 14 | US10457647, Example 14 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259416(US9512084, 15 | US10457647, Example 15 | US1118046...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259402(US9512084, 1 | US10457647, Example 1 | US11180460,...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259422(US9512084, 21 | US10457647, Example 21 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259432(US9512084, 31 | US10457647, Example 31 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259435(US9512084, 34 | US10457647, Example 34 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259436(US9512084, 35 | US10457647, Example 35 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259439(US9512084, 38 | US10457647, Example 38 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259441(US9512084, 40 | US10457647, Example 40 | US1118046...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259409(US9512084, 8 | US10457647, Example 8 | US11180460,...)
Affinity DataIC50: 2nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259428(US9512084, 27 | US10457647, Example 27 | US1118046...)
Affinity DataIC50: 3nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259430(US9512084, 29 | US10457647, Example 29 | US1118046...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259411(US9512084, 10 | US10457647, Example 10 | US1118046...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259433(US9512084, 32 | US10457647, Example 32 | US1118046...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259406(US9512084, 5 | US10457647, Example 5 | US11180460,...)
Affinity DataIC50: 4nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259421(US9512084, 20 | US10457647, Example 20 | US1118046...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259418(US9512084, 17 | US10457647, Example 17 | US1118046...)
Affinity DataIC50: 5nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259431(US9512084, 30 | US10457647, Example 30 | US1118046...)
Affinity DataIC50: 6nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259414(US9512084, 13 | US10457647, Example 13 | US1118046...)
Affinity DataIC50: 7nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
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TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259405(US9512084, 4 | US10457647, Example 4 | US11180460,...)
Affinity DataIC50: 9nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259412(US9512084, 11 | US10457647, Example 11 | US1118046...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259410(US9512084, 9 | US10457647, Example 9 | US11180460,...)
Affinity DataIC50: 10nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259413(US9512084, 12 | US10457647, Example 12 | US1118046...)
Affinity DataIC50: 12nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259417(US9512084, 16 | US10457647, Example 16 | US1118046...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259420(US9512084, 19 | US10457647, Example 19 | US1118046...)
Affinity DataIC50: 16nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259437(US9512084, 36 | US10457647, Example 36 | US1118046...)
Affinity DataIC50: 17nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259438(US9512084, 37 | US10457647, Example 37 | US1118046...)
Affinity DataIC50: 32nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259403(US9512084, 2 | US10457647, Example 2 | US11180460,...)
Affinity DataIC50: 38nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM259408(US9512084, 7 | US10457647, Example 7 | US11180460,...)
Affinity DataIC50: 42nMAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent