Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8718
TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380039(US9926301, Example 1 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2020
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380063(US9926301, Example 2 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
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Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM246853(4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380422(US9926301, Example 3 | 4-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380449(US9926301, Example 13 | 4-{3-(Cyanomethyl)-3-[3-(h...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380426(US9926301, Example 4 | 4-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380442(US9926301, Example 6 | 5-[3-(Cyanomethyl)-3-(3,3&#...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM246853(4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM380445(US9926301, Example 9 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380444(US9926301, Example 8 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 300nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
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US Patent
LigandPNGBDBM246853(4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
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US Patent
LigandPNGBDBM380448(US9926301, Example 12 | 4-{3-(Cyanomethyl)-3-[3...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM380447(US9926301, Example 11 | 5-[3-(Cyanomethyl)-3-(3...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM380446(US9926301, Example 10 | 5-[3-(Cyanomethyl)-3-(3-me...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380445(US9926301, Example 9 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380444(US9926301, Example 8 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM246853(4-[3-(cyanomethyl)- 3-(3',5'-dimethyl- 1H,...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1 [837-1142](Human)
Incyte

US Patent
LigandPNGBDBM380441(US9926301, Example 5 | 4-[3-(1H,1′H-4,4̸...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380426(US9926301, Example 4 | 4-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380063(US9926301, Example 2 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 650nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380039(US9926301, Example 1 | 5-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 700nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
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TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380442(US9926301, Example 6 | 5-[3-(Cyanomethyl)-3-(3,3&#...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380441(US9926301, Example 5 | 4-[3-(1H,1′H-4,4̸...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380446(US9926301, Example 10 | 5-[3-(Cyanomethyl)-3-(3-me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380447(US9926301, Example 11 | 5-[3-(Cyanomethyl)-3-(3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380448(US9926301, Example 12 | 4-{3-(Cyanomethyl)-3-[3...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380422(US9926301, Example 3 | 4-[3-(Cyanomethyl)-3-(3R...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2 [828-1132](Human)
Incyte

US Patent
LigandPNGBDBM380449(US9926301, Example 13 | 4-{3-(Cyanomethyl)-3-[3-(h...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds herein were tested for inhibitory activity of JAK targets according to the following in vitro assay described in Park et al., Analytical Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent