Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 3373
TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM50197614(CHEMBL3939323 | US10322140, Example 12)
Affinity DataIC50: 0.990nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398052(US10322140, Example 3 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 1.22nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398050(US10322140, Example 2 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 1.34nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398061(US10322140, Example 6 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 2.07nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM50197581(CHEMBL3929336 | US10322140, Example 4)
Affinity DataIC50: 3.08nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398062(US10322140, Example 7 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 5.01nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398049(US10322140, Example 13)
Affinity DataIC50: 6.20nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398064(US10322140, Example 11 | 2-(6-((E)-2- ((3R,3aS,4R,...)
Affinity DataIC50: 6.30nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398044(US10322140, Example 9)
Affinity DataIC50: 14.5nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM398063(US10322140, Example 10 | 2-(6-((E)-2- ((3R,3aS,4R,...)
Affinity DataIC50: 25.3nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetProteinase-activated receptor 1(Human)
TBA

US Patent
LigandPNGBDBM50197612(CHEMBL3968866 | US10322140, Example 8)
Affinity DataIC50: 28.7nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM50197614(CHEMBL3939323 | US10322140, Example 12)
Affinity DataIC50: 2.40E+3nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398049(US10322140, Example 13)
Affinity DataIC50: 8.80E+3nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM50197581(CHEMBL3929336 | US10322140, Example 4)
Affinity DataIC50: 9.90E+3nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398052(US10322140, Example 3 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 1.04E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398067(US10322140, Example 5)
Affinity DataIC50: 1.69E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398064(US10322140, Example 11 | 2-(6-((E)-2- ((3R,3aS,4R,...)
Affinity DataIC50: 1.76E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM50197613(CHEMBL3940415 | US10322140, Example 1)
Affinity DataIC50: 2.18E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398050(US10322140, Example 2 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 2.28E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398061(US10322140, Example 6 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398062(US10322140, Example 7 | 2-(6-((E)-2- ((3R,3aS,4R,5...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM50197612(CHEMBL3968866 | US10322140, Example 8)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398044(US10322140, Example 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM398063(US10322140, Example 10 | 2-(6-((E)-2- ((3R,3aS,4R,...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound dilutions and assay-ready plates were prepared on a TTP Labtech mosquito HTS. Assay conduction was fully automated on a customized Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
Go to US Patent