Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 2577
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372300(US10239887, Cpd. No. 38 | 8-chloro-N-cyclopropyl- ...)
Affinity DataEC50:  56.5nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372313(US10239887, Cpd. No. 50 | 8-chloro-N-cyclopentyl-7...)
Affinity DataEC50:  593nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372312(US10239887, Cpd. No. 49 | 8-chloro-N-cyclobutyl- 7...)
Affinity DataEC50:  695nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372311(US10239887, Cpd. No. 48 | 8-chloro-7,9-dimethyl- 4...)
Affinity DataEC50:  2.53E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372310(US10239887, Cpd. No. 47 | 8-chloro-N-ethyl- 7,9-di...)
Affinity DataEC50:  1.25E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372309(US10239887, Cpd. No. 46 | 8-chloro-N-isobutyl- 7,9...)
Affinity DataEC50:  601nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372307(US10239887, Cpd. No. 45 | 8-chloro-7,9-dimethyl-N-...)
Affinity DataEC50:  358nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372306(US10239887, Cpd. No. 44 | 8-chloro-N,7,9-trimethyl...)
Affinity DataEC50:  1.69E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372305(US10239887, Cpd. No. 43 | 8-chloro-N,N,7,9- tetram...)
Affinity DataEC50:  1.39E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372304(US10239887, Cpd. No. 42 | 4-(azetidin-1-yl)-8- chl...)
Affinity DataEC50:  269nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372303(US10239887, Cpd. No. 41 | 8-chloro-N- (2-ethylcycl...)
Affinity DataEC50:  324nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372302(US10239887, Cpd. No. 40 | 8-chloro-N-(2,2- dimethy...)
Affinity DataEC50:  109nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372301(US10239887, Cpd. No. 39 | 2-[4-[[(8-chloro-7,9- di...)
Affinity DataEC50:  110nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372314(US10239887, Cpd. No. 51 | 8-chloro-N-[2-(3,4- difl...)
Affinity DataEC50:  7.84E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372299(US10239887, Cpd. No. 37 | 8-chloro-N-(3,3-difluoro...)
Affinity DataEC50:  406nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372298(US10239887, Cpd. No. 36)
Affinity DataEC50:  1.00E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372297(US10239887, Cpd. No. 35 | 1-(3-((3,4- dimethylpyri...)
Affinity DataEC50:  53nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372296(US10239887, Cpd. No. 34 | 1-(3,4-dimethylpyrimido ...)
Affinity DataEC50:  660nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372295(3,4-dimethyl-8-(3- phenoxyazetidin-1-yl) pyrimido[...)
Affinity DataEC50:  4.43E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372294(8-(3-(3-fluorophenoxy) azetidin-1-yl)-3,4- dimethy...)
Affinity DataEC50:  1.76E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372293(8-(3-(2-fluorophenoxy) azetidin-1-yl)-3,4- dimethy...)
Affinity DataEC50:  2.16E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372292(8-(3-(4-fluorophenoxy) azetidin-1-yl)-3,4- dimethy...)
Affinity DataEC50:  2.61E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372291(N-(4-(2-fluoropyridin- 3-yl)benzyl)-3,4- dimethylp...)
Affinity DataEC50:  4.05E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372290(3,4-dimethyl-8-(3- phenylpyrrolidin-1-yl) pyrimido...)
Affinity DataEC50:  3.56E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372289(N-(3-fluoro-4- methoxybenzyl)-3,4- dimethylpyrimid...)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372327(US10239887, Cpd. No. 64 | 1-[4-[[(3,4- dimethylpyr...)
Affinity DataEC50:  862nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372338(US10239887, Cpd. No. 75 | N-[(3-fluoro-4-methoxy- ...)
Affinity DataEC50:  1.07E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372337(US10239887, Cpd. No. 74 | 2-[5-[[(3,4- dimethylpyr...)
Affinity DataEC50:  9.16E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372336(US10239887, Cpd. No. 73 | 3,4-dimethyl-8-(2-oxa-6-...)
Affinity DataEC50:  4.84E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372335(US10239887, Cpd. No. 72 | N-(3,3-difluorocyclobuty...)
Affinity DataEC50:  1.75E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372334(US10239887, Cpd. No. 71 | 3,4-dimethyl-N-(2- oxasp...)
Affinity DataEC50: >1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372333(US10239887, Cpd. No. 70 | N-cyclopentyl-3,4- dimet...)
Affinity DataEC50:  818nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372332(US10239887, Cpd. No. 69 | N-cyclobutyl-3,4- dimeth...)
Affinity DataEC50:  1.53E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372331(US10239887, Cpd. No. 68 | N-cyclopropyl-3,4- dimet...)
Affinity DataEC50:  1.31E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372330(US10239887, Cpd. No. 67 | 2-[3-[[(3,4- dimethylpyr...)
Affinity DataEC50:  1.70E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372329(US10239887, Cpd. No. 66 | 1-[3-[[(3,4- dimethylpyr...)
Affinity DataEC50:  1.36E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372328(US10239887, Cpd. No. 65 | 2-[4-[[(3,4-dimethylpyri...)
Affinity DataEC50:  2.29E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372288(N-(2-(4-methoxyphenyl) cyclopropyl)-3,4- dimethylp...)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372326(US10239887, Cpd. No. 63 | N-[1-(5-Fluoropyrimidin-...)
Affinity DataEC50:  284nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372325(US10239887, Cpd. No. 62 | N-cyclopropyl-7,9-dimeth...)
Affinity DataEC50:  2.60E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372324(US10239887, Cpd. No. 61 | N-[2-(3,4-dichloro- phen...)
Affinity DataEC50:  3.38E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372323(US10239887, Cpd. No. 60 | N-[1-(2,5-dichloro-4- py...)
Affinity DataEC50:  1.49E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372322(US10239887, Cpd. No. 59 | N-[1-(5-fluoropyrimidin-...)
Affinity DataEC50:  2.11E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372320(US10239887, Cpd. No. 57 | 2-[3-[[(7,9- dimethylpyr...)
Affinity DataEC50:  4.27E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372319(US10239887, Cpd. No. 56 | 7,9-dimethyl-4-(2-oxa-6-...)
Affinity DataEC50:  3.37E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372318(US10239887, Cpd. No. 55 | N-Cyclobutyl-7,9-dimethy...)
Affinity DataEC50:  1.59E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372317(US10239887, Cpd. No. 54 | 8-chloro-7,9-dimethyl-N-...)
Affinity DataEC50:  1.19E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372316(US10239887, Cpd. No. 53 | 8-chloro-N-(3- methoxypr...)
Affinity DataEC50:  365nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372315(US10239887, Cpd. No. 52 | 8-chloro-N-(cyclobutyl- ...)
Affinity DataEC50:  1.53E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM372266(3,4-dimethyl-8-(pyrrolidin-1- yl)pyrimido[4',5':4,...)
Affinity DataEC50:  48nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent

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