Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 2475
TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367647(US10227312, Example 32 | 8-chloro-N-((1R,2R)-1-(3-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367635(US10227312, Example 20 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367637(US10227312, Example 22 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367640(US10227312, Example 25 | N-((1R,2R)-1-(4-cycloprop...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367641(US10227312, Example 26 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367642(US10227312, Example 27 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367643(US10227312, Example 28 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367644(US10227312, Example 29 | N-((1R,2R)-1-(4-cycloprop...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367645(US10227312, Example 30 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367617(US10227312, Example 2 | N-((1R,2R)-1-(4-cyclopropo...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367648(US10227312, Example 33 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367649(US10227312, Example 34 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367650(US10227312, Example 36 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367651(US10227312, Example 37 | 2-chloro-N-((1R,2R)-1-(3-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367659(US10227312, Example 45 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367660(US10227312, Example 46 | N-((1R,2R)-1-(4-cycloprop...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367661(US10227312, Example 47 | 2-chloro-N-((1R,2R)-1-(4-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367624(US10227312, Example 9 | N-((1R,2R)-3-(azetidin-1-y...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367616(US10227312, Example 1 | N-((1R,2R)-1-(3-chloro-4- ...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367618(US10227312, Example 3 | N-((1R,2R)-1-(8-fluoro-2,3...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367622(US10227312, Example 7 | N-((1R,2R)-3-(azetidin-1-y...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367623(US10227312, Example 8 | 7-(5-chlorothiophen-2-yl)-...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367629(US10227312, Example 14 | 7-(5-chlorothiophen-2-yl)...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367632(US10227312, Example 17 | N-((1R,2R)-1-(4-cycloprop...)
Affinity DataIC50: 5.5nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367621(US10227312, Example 6 | N-((1R,2R)-3-(azetidin-1-y...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367634(US10227312, Example 19 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367619(US10227312, Example 4 | N-((1R,2R)-1-(4-cyclopropo...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367658(US10227312, Example 44 | 8-chloro-N-((1R,2R)-1-(4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367654(US10227312, Example 40 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367653(US10227312, Example 39 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367652(US10227312, Example 38 | N-((1R,2R)-1-(4-cycloprop...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367620(US10227312, Example 5 | N-((1R,2R)-3-(azetidin-1-y...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367639(US10227312, Example 24 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367636(US10227312, Example 21 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367633(US10227312, Example 18 | 7-(5-chlorothiophen-2-yl)...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367646(US10227312, Example 31 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367625(US10227312, Example 10 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367626(US10227312, Example 11 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367627(US10227312, Example 12 | 7-chloro-N-((1R,2R)-1-(4-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367628(US10227312, Example 13 | 7-chloro-N-((1R,2R)-1-(3-...)
Affinity DataIC50: 55nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367631(US10227312, Example 16 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367655(US10227312, Example 41 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367656(US10227312, Example 42 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367657(US10227312, Example 43 | 7-chloro-N-((1R,2R)-1-(3-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367638(US10227312, Example 23 | N-((1R,2R)-1-(3-chloro-4-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCeramide glucosyltransferase(Human)
Biomarin Pharmaceutical

US Patent
LigandPNGBDBM367630(US10227312, Example 15 | N-((1R,2R)-3-(azetidin-1-...)
Affinity DataIC50: 550nMAssay Description:This assay was modified based on the study by Larsen et al. (J. Lipid Res. 2011, 53, 282). Madin-Darby canine kidney (MDCK) cell lysate was prepared ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent