Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 2321
TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361628(US10221175, Compound 33)
Affinity DataEC50:  2.20E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361618(US10221175, Compound 23)
Affinity DataEC50:  1.35E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361619(US10221175, Compound 24)
Affinity DataEC50:  3.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361620(US10221175, Compound 25)
Affinity DataEC50:  3.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361621(US10221175, Compound 26)
Affinity DataEC50:  3.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361622(US10221175, Compound 27)
Affinity DataEC50:  2.26E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361623(US10221175, Compound 28)
Affinity DataEC50:  2.37E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361624(US10221175, Compound 29)
Affinity DataEC50:  3.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361625(US10221175, Compound 30)
Affinity DataEC50:  677nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361626(US10221175, Compound 31)
Affinity DataEC50:  1.63E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361627(US10221175, Compound 32)
Affinity DataEC50:  1.40E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361617(US10221175, Compound 22)
Affinity DataEC50:  1.31E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361629(US10221175, Compound 34)
Affinity DataEC50:  3.90E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361630(US10221175, Compound 35)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361631(US10221175, Compound 36)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361632(US10221175, Compound 37)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361633(US10221175, Compound 38)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361634(US10221175, Compound 39)
Affinity DataEC50:  857nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361635(US10221175, Compound 40)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361636(US10221175, Compound 41)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361637(US10221175, Compound 42)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361607(US10221175, Compound 12)
Affinity DataEC50:  3.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361597(A. Preparation of 7-(2-fluoro-4-(2-methyl-2H-indaz...)
Affinity DataEC50:  688nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361598(US10221175, Compound 3)
Affinity DataEC50:  656nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361599(US10221175, Compound 4)
Affinity DataEC50:  1.75E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361600(US10221175, Compound 5)
Affinity DataEC50:  743nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361601(US10221175, Compound 6)
Affinity DataEC50:  488nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361602(US10221175, Compound 7)
Affinity DataEC50:  2.64E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361603(US10221175, Compound 8)
Affinity DataEC50:  1.06E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361604(A. Preparation of 7-(2-fluoro-4-(2-methyl-2H-indaz...)
Affinity DataEC50:  502nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361605(US10221175, Compound 10)
Affinity DataEC50:  1.57E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361606(US10221175, Compound 11)
Affinity DataEC50:  856nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361596(A. Preparation of 7-(2,6-difluoro-4-(2-methyl-2h-i...)
Affinity DataEC50:  952nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361608(US10221175, Compound 13)
Affinity DataEC50:  1.82E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361609(US10221175, Compound 14)
Affinity DataEC50:  1.79E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361610(US10221175, Compound 15)
Affinity DataEC50:  1.24E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361611(US10221175, Compound 16)
Affinity DataEC50:  1.21E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361612(US10221175, Compound 17)
Affinity DataEC50:  618nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361613(US10221175, Compound 18)
Affinity DataEC50:  2.14E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361614(US10221175, Compound 19)
Affinity DataEC50:  1.41E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361615(US10221175, Compound 20)
Affinity DataEC50:  2.10E+3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361616(US10221175, Compound 21)
Affinity DataEC50:  1.00E+4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent