Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2261
TargetCytochrome P450 3A4(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 8.00E+3nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetCytochrome P450 2C19(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 8.20E+3nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetCytochrome P450 3A4(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM234945(US9556143, Voriconazole | US9556143, 31 | US102211...)
Affinity DataIC50: 1.30E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetCytochrome P450 2C9(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM234945(US9556143, Voriconazole | US9556143, 31 | US102211...)
Affinity DataIC50: 1.40E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetCytochrome P450 2C19(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM234945(US9556143, Voriconazole | US9556143, 31 | US102211...)
Affinity DataIC50: 1.50E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124182(US8754227, 1 | US10221160, Example 1 | US11247981,...)
Affinity DataIC50: 1.60E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 2.90E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124182(US8754227, 1 | US10221160, Example 1 | US11247981,...)
Affinity DataIC50: 3.50E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124182(US8754227, 1 | US10221160, Example 1 | US11247981,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124183(US8754227, 2 | US10221160, Example 2 | US11247981,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124183(US8754227, 2 | US10221160, Example 2 | US11247981,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Mycovia Pharmaceuticals

US Patent
LigandPNGBDBM124183(US8754227, 2 | US10221160, Example 2 | US11247981,...)
Affinity DataIC50: 6.00E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent