Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 2000
TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350280(US10208060, Example 13 | 2-(4-Hydroxy-2-oxo-1-(3'-...)
Affinity DataIC50: 4.10nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350271(US10208060, Example 2 | 2-(1-(4-chlorophenyl)-4- h...)
Affinity DataIC50: 7.80nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350273(US10208060, Example 4 | 2-(4-hydroxy-2-oxo-1-pheny...)
Affinity DataIC50: 8.5nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350276(US10208060, Example 7 | 2-(4-hydroxy-2-oxo-1-(m- t...)
Affinity DataIC50: 8.60nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350278(US10208060, Example 9 | 2-(1-(4-cyanophenyl)-4- hy...)
Affinity DataIC50: 9.5nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350277(US10208060, Example 8 | 2-(4-hydroxy-2-oxo-1-(p- t...)
Affinity DataIC50: 10nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350274(US10208060, Example 5 | 2-(4-hydroxy-1-(4- methoxy...)
Affinity DataIC50: 11.4nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350275(US10208060, Example 6 | 2-(4-hydroxy-2-oxo-1-(4- (...)
Affinity DataIC50: 13.4nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350272(US10208060, Example 3 | 2-(1-(4-fluorophenyl)-4- h...)
Affinity DataIC50: 14.1nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
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TargetEgl nine homolog 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM350279(US10208060, Example 10 | 2-(4-hydroxy-1-(5- methox...)
Affinity DataIC50: 14.2nMAssay Description:To each well of a 384-well plate, 1 μL of test compounds in DMSO (final concentration ranging from 0.3 nM to 10 uM) were added into 20 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2019
Entry Details
Go to US Patent