Compile Data Set for Download or QSAR
Report error Found 347 Enz. Inhib. hit(s) with all data for entry = 1584
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332053(US10189854, Compound 1 | [1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332054(US10189854, Compound 2 | 1-[5-(2-Fluorophenyl)-pyr...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332055(US10189854, Compound 3 | [1-[5-(1-Fluorophenyl)-py...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332056(US10189854, Compound 4 | 4-[1-[5-(2-Fluorophenyl)-...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332057(US10189854, Compound 5 | [1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332059(US10189854, Compound 7 | Morpholin-4-yl-[1-(5-phen...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332060(US10189854, Compound 8 | [1-[5-(2,4-Difluoro-pheny...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332062(US10189854, Compound 12 | Morpholin-4-yl-[1-(5-o-t...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332063(US10189854, Compound 15 | [1-[5-(2,3-Difluoro-phen...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332064(US10189854, Compound 16 | [1-[5-(2-Fluoro-5-methox...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332065(US10189854, Compound 17 | [1-[5-(2-Fluoro-4-methox...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332070(US10189854, Compound 22 | 4-Fluoro-3-[2-[6-(morpho...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332071(US10189854, Compound 23 | [1-[5-[2-Fluoro-5-(trifl...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332074(US10189854, Compound 26 | 3-Fluoro-4-[2-[6-(morpho...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332075(US10189854, Compound 27 | [1-[5-(2,6-Difluoro-phen...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332077(US10189854, Compound 29 | [1-[5-(2-Fluoro-4-methyl...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332079(US10189854, Compound 31 | [1-[5-(2-Methoxyphenyl)-...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332081(US10189854, Compound 34 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332082(US10189854, Compound 35 | 4-Fluoro-3-[2-[6-(morpho...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332084(US10189854, Compound 38 | 4-[1-[5-(2-Fluorophenyl)...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332086(US10189854, Compound 40 | [(3R)-3-Amino-pyrrolidin...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332087(US10189854, Compound 41 | N-(2-Amino-ethyl)-1-[5-(...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332088(US10189854, Compound 42 | [1-[5-(2-Fluoro-5-methyl...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332089(US10189854, Compound 43 | [1-[5-(4-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332090(US10189854, Compound 44 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332094(US10189854, Compound 48 | [1-[5-(3-Methoxyphenyl)-...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332095(US10189854, Compound 49 | [1-(5-Phenyl-pyrimidin-2...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332096(US10189854, Compound 50 | [1-[5-(3,5-Difluoro-phen...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332098(US10189854, Compound 52 | [1-[5-(2-Fluoro-5-methyl...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332100(US10189854, Compound 54 | 3-[2-[6-(Morpholine-4-ca...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332101(US10189854, Compound 55 | 4-[1-(5-Phenyl-pyrimidin...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332102(US10189854, Compound 56 | 3-[2-[6-(Morpholine-4-ca...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332103(US10189854, Compound 57 | [1-[5-(3-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332104(US10189854, Compound 58 | [1-[5-(5-Chloro-2-fluoro...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332105(US10189854, Compound 59 | [1-(5-Phenyl-pyrimidin-2...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332106(US10189854, Compound 60 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332109(US10189854, Compound 63 | 4-[2-[6-(Morpholine-4-ca...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332111(US10189854, Compound 65 | 3-Fluoro-N,N-dimethyl-4-...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332118(US10189854, Compound 72 | [1-[5-[2-Fluoro-5-(trifl...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332119(US10189854, Compound 73 | [1-[5-(2-Fluoro-5-methox...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332128(US10189854, Compound 84 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332129(US10189854, Compound 85 | 1-[5-[1-[5-(2-Fluorophen...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332137(US10189854, Compound 93 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332081(US10189854, Compound 34 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332139(US10189854, Compound 95 | 1-[5-(2-Fluorophenyl)-py...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332140(US10189854, Compound 96 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332143(US10189854, Compound 99 | N-[2-(Dimethylamino)ethy...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332147(US10189854, Compound 103 | [1-[5-(2-Fluorophenyl)-...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332148(US10189854, Compound 104 | [(2R,6S)-2,6-dimethyl-m...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Gruenenthal

US Patent
LigandPNGBDBM332151(US10189854, Compound 107 | (2,5-Diazabicyclo[2.2.1...)
Affinity DataIC50: 100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

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