Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 1298
TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 8nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM50043906(CHEMBL269001 | Dorzolamide | MK-507 | US10172837, ...)
Affinity DataIC50: 9nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 12nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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PDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM315269(US10172837, Methazolamide)
Affinity DataIC50: 14nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM10888(Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonam...)
Affinity DataIC50: 35nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM10883(Dichlorophenamide, DCP | CHEMBL17 | Sulfonamide, 4...)
Affinity DataIC50: 38nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM11638(N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sul...)
Affinity DataIC50: 40nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataIC50: 80nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM25900(Hygroton | Chlortalidone | 2-chloro-5-(1-hydroxy-3...)
Affinity DataIC50: 260nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM10855(orthanilamide 17 | CHEMBL6705 | 2-aminobenzene-1-s...)
Affinity DataIC50: 295nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
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TargetCarbonic anhydrase 1(Human)
Naia Metabolic

US Patent
LigandPNGBDBM39351(MLS000028398 | cid_2720 | SMR000058429 | CHLOROTHI...)
Affinity DataIC50: 460nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent