Compile Data Set for Download or QSAR
Report error Found 409 Enz. Inhib. hit(s) with all data for entry = 1241
LigandPNGBDBM313641(US10167279, Example 267 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 5nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313647(US10167279, Example 273 | (R)-N-(3-(2-(2,3- dihydr...)
Affinity DataIC50: 10nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313464(N-(5'-(3-fluorooxetan-3- yl)-6'-methoxy-2- methyl-...)
Affinity DataIC50: 13.6nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313390(N-(3-(2-(3- (difluoromethyl)oxetan- 3-yl)-6-(2- hy...)
Affinity DataIC50: 15.5nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313568(US10167279, Example 194 | US10167279, Example 193 ...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313580(N-(3-(2- (hydroxymethyl)-2- methyl-3-oxo-8- (tetra...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313601(2-(1,1-difluoroethyl)-N- (3-(6-ethoxy-5- (tetrahyd...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313632(US10167279, Example 258 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313642(US10167279, Example 268 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313645(US10167279, Example 271 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313683(US10167279, Example 309 | (S)-N-(3-(6-((1- hydroxy...)
Affinity DataIC50: 20nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313571(N-(3-(2- (hydroxymethyl)- 2-methyl-3-oxo-5- (tetra...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313608(N-(3-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313635(US10167279, Example 261 | 4-chloro-N-(3-(2-(2- hyd...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313643(US10167279, Example 269 | 2-(1,1-difluoroethyl)-N-...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313648(US10167279, Example 274 | (R)-N-(3-(2-(2,3- dihydr...)
Affinity DataIC50: 30nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313532(N-(3-(2-((2- hydroxyethyl)amino)-6- (3-methoxyoxet...)
Affinity DataIC50: 40nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313533(N-(3-(2-((2- hydroxyethyl)amino)-6- (3-methoxyoxet...)
Affinity DataIC50: 40nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313614(N-(3-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 40nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313615(N-(3-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 40nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313684(US10167279, Example 310 | (R)-N-(3-(6-((1- hydroxy...)
Affinity DataIC50: 40nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313646(US10167279, Example 272 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313652(US10167279, Example 278 | (R)-4-chloro-N-(3-(2- (2...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313655(US10167279, Example 281 | (R)-N-(3-(2-(2,3- dihydr...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313685(US10167279, Example 311 | (S)-N-(3-(6-((2- hydroxy...)
Affinity DataIC50: 50nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313464(N-(5'-(3-fluorooxetan-3- yl)-6'-methoxy-2- methyl-...)
Affinity DataIC50: 59.3nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313604(5-chloro-N-(3-(6- ethoxy-5-(tetrahydro- 2H-pyran-4...)
Affinity DataIC50: 60nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313650(US10167279, Example 276 | (R)-N-(3-(2-(2,3- dihydr...)
Affinity DataIC50: 60nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313688(US10167279, Example 314 | N-(3-(6-((1- ethylpiperi...)
Affinity DataIC50: 60nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313568(US10167279, Example 194 | US10167279, Example 193 ...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313613(N-(3-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313653(US10167279, Example 279 | (R)-2-cyano-N-(3-(2-(2,3...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313654(US10167279, Example 280 | (R)-2-chloro-N-(3-(2- (2...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313657(US10167279, Example 283 | (R)-N-(3-(2-(2,3- dihydr...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313687(US10167279, Example 313 | N-(4-methyl-3-(5-tetrahy...)
Affinity DataIC50: 70nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313387(2-(difluoromethyl)-N- (3-(2-(3- (fluoromethyl)oxet...)
Affinity DataIC50: 74.7nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313400(N-(3-(6-ethoxy-5-(3- methyloxetan-3- yl)pyridin-3-...)
Affinity DataIC50: 78nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313531(N-(2'-((2- hydroxyethyl)amino)-6'- (3-methoxyoxeta...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313588(N-(3-(2-(4- (fluoromethyl)tetrahydro- 2H-pyran-4-y...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313610(N-(5-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313634(US10167279, Example 260 | N-(3-(2-(2- hydroxyethox...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313681(US10167279, Example 307 | N-(3-(6-((2-methoxyethyl...)
Affinity DataIC50: 80nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313484(2-(1,1-difluoroethyl)-N- (3-(5-(3- (fluoromethyl)o...)
Affinity DataIC50: 84.4nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313512(N-(2'-(3- (fluoromethyl)oxetan-3- yl)-6'-(2- hydro...)
Affinity DataIC50: 85.3nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313644(US10167279, Example 270 | 2-(2-cyanopropan-2-yl)- ...)
Affinity DataIC50: 90nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313695(US10167279, Example 321 | N-(3-(2-(4-amino-4-methy...)
Affinity DataIC50: 90nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313486(N-(3-(5-(3- (fluoromethyl)oxetan-3- yl)-6-methoxyp...)
Affinity DataIC50: 91.5nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313567(2-(1,1-difluoroethyl)-N- (3-(2-(hydroxymethyl)- 2-...)
Affinity DataIC50: 100nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313577(N-(3-(2- (hydroxymethyl)-2- methyl-3-oxo-8- (tetra...)
Affinity DataIC50: 100nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM313583(N-(3-(2-(2- hydroxyethoxy)-6-(4- methyltetrahydro-...)
Affinity DataIC50: 100nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent

Displayed 1 to 50 (of 409 total ) | Next | Last >>
Jump to: