Compile Data Set for Download or QSAR
Report error Found 178 Enz. Inhib. hit(s) with all data for entry = 1121
TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310612(US10150762, Example 1 | 5-(4-(1,1,3,3,3-Hexafluoro...)
Affinity DataKd:  5.60nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
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Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310613(US10150762, Example 2 | US10150762, Example 2/3a |...)
Affinity DataKd:  5.70nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310614(US10150762, Example 2/1)
Affinity DataKd:  0.160nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310615(US10150762, Example 2/2)
Affinity DataKd:  0.220nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310613(US10150762, Example 2 | US10150762, Example 2/3a |...)
Affinity DataKd:  4.90nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310613(US10150762, Example 2 | US10150762, Example 2/3a |...)
Affinity DataKd:  7.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310618(US10150762, Example 2/3c)
Affinity DataKd:  5.5nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310619(US10150762, Example 2/4)
Affinity DataKd:  3.70nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310620(US10150762, Example 2/5)
Affinity DataKd:  0.670nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
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Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310621(US10150762, Example 2/6)
Affinity DataKd:  3.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310622(US10150762, Example 2/7)
Affinity DataKd:  0.560nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310623(US10150762, Example 2/8)
Affinity DataKd:  0.300nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310624(US10150762, Example 2/9)
Affinity DataKd:  27nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310625(US10150762, Example 2/10)
Affinity DataKd:  13nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310626(US10150762, Example 2/11)
Affinity DataKd:  6.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310627(US10150762, Example 2/12)
Affinity DataKd:  18nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310628(US10150762, Example 2/13)
Affinity DataKd:  0.430nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
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Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310629(US10150762, Example 2/14)
Affinity DataKd:  44nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310630(US10150762, Example 2/15)
Affinity DataKd:  0.180nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310632(US10150762, Example 3 | 5-(2,3-Dichloro-4-(1,1,1,3...)
Affinity DataKd:  4.60nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310633(US10150762, Example 3/1)
Affinity DataKd:  11nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310634(US10150762, Example 3/2)
Affinity DataKd:  9.70nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310632(US10150762, Example 3 | 5-(2,3-Dichloro-4-(1,1,1,3...)
Affinity DataKd:  17nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310636(US10150762, Example 3/3b)
Affinity DataKd:  3.60nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310637(US10150762, Example 3/4)
Affinity DataKd:  10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310638(US10150762, Example 3/5)
Affinity DataKd:  50nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310639(US10150762, Example 3/6)
Affinity DataKd:  22nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310640(US10150762, Example 3/7)
Affinity DataKd:  34nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310641(US10150762, Example 3/8)
Affinity DataKd:  38nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310642(US10150762, Example 3/9)
Affinity DataKd:  19nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310643(US10150762, Example 3/10 | 4-(4-(7-Azabicyclo[2.2....)
Affinity DataKd:  24nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310644(US10150762, Example 3/11 | 4-(4-(7-Azabicyclo[2.2....)
Affinity DataKd:  68nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310645(US10150762, Example 4 | 5-(2,3-Dichloro-4-(1,1,1,3...)
Affinity DataKd:  410nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310646(US10150762, Example 5 | 5-(2,3-Dichloro-4-(1,1,1,3...)
Affinity DataKd:  2.90nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310647(US10150762, Example 6 | (5-(2,3-Dichloro-4-(1,1,1,...)
Affinity DataKd:  3.80nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310648(US10150762, Example 6/1)
Affinity DataKd:  2.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310649(US10150762, Example 6/2)
Affinity DataKd:  11nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310650(US10150762, Example 7 | 5-(3-(tert-Butyl)-5-(1,1,1...)
Affinity DataKd:  2.70nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310651(US10150762, Example 8 | (5-(2,3-Dichloro-4-(1,1,1,...)
Affinity DataKd:  0.150nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310652(US10150762, Example 9 | ((S)-4,4-Difluoro-2-methyl...)
Affinity DataKd:  0.0700nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310653(US10150762, Example 9/1 | ((S)-4,4-Difluoro-2-meth...)
Affinity DataKd:  0.110nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310654(US10150762, Example 9/2 | ((S)-4,4-Difluoro-2-meth...)
Affinity DataKd:  0.110nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310655(US10150762, Example 9/3 | N4,N4-Diethyl-5-(2-ethyl...)
Affinity DataKd:  8nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310656(US10150762, Example 9/4 | N4,N4-Diethyl-5-(4-(1,1,...)
Affinity DataKd:  3.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310657(US10150762, Example 9/5 | 5-(2-Chloro-3-fluoro-4-(...)
Affinity DataKd:  33nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310658(US10150762, Example 10 | (4-(7-Azabicyclo[2.2.11]h...)
Affinity DataKd:  2.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310659(US10150762, Example 10/1 | (4-(7-Azabicyclo[2.2.1]...)
Affinity DataKd:  26nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310660(US10150762, Example 10/2 | 4-(7-Azabicyclo[2.2.1]h...)
Affinity DataKd:  3.20nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310661(US10150762, Example 10/3 | (S)-(5-(2-Chloro-4-(1,1...)
Affinity DataKd:  2.5nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310662(US10150762, Example 10/4 | (S)-5-(4-(1,1,1,3,3,3-H...)
Affinity DataKd:  1.40nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
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