Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 865
TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 2nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 5.10nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228728(US9346810, 94 | US10111875, Compound 142 | US10369...)
Affinity DataIC50: 9.40nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228644(US9346810, 105 | US10111875, Compound 105 | US1036...)
Affinity DataIC50: 14nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294510(US10111875, Compound 199)
Affinity DataIC50: 14nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 41.1nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294511(US10111875, Compound 206 | US10369153, Compound 20...)
Affinity DataIC50: 47nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228644(US9346810, 105 | US10111875, Compound 105 | US1036...)
Affinity DataIC50: 48.7nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228728(US9346810, 94 | US10111875, Compound 142 | US10369...)
Affinity DataIC50: 55nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294510(US10111875, Compound 199)
Affinity DataIC50: 75nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228640(US9346810, 234 | US10111875, Compound 234 | US1036...)
Affinity DataIC50: 86.3nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK2(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228645(US9346810, 47 | US10111875, Compound 47 | US103691...)
Affinity DataIC50: 98nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK1(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228645(US9346810, 47 | US10111875, Compound 47 | US103691...)
Affinity DataIC50: 119nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228645(US9346810, 47 | US10111875, Compound 47 | US103691...)
Affinity DataIC50: 157nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228644(US9346810, 105 | US10111875, Compound 105 | US1036...)
Affinity DataIC50: 359nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM228728(US9346810, 94 | US10111875, Compound 142 | US10369...)
Affinity DataIC50: 497nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hutchinson Medipharma

US Patent
LigandPNGBDBM294510(US10111875, Compound 199)
Affinity DataIC50: 522nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent