Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 235
TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243356(5-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243366(4-{5-[3-(Thiazol-2- ylamino)-phenyl]oxazol- 2-yl}-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243363(4-{5-[3-(4-Pyridin-3-yl- pyrimidin-2-ylamino)- phe...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243362(4-{5-[2-Fluoro-5-(4- methyl-pyrimidin-2- ylamino)-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243361(4-{5-[2-(2-Morpholin-4- yl-ethoxy)-5-(4- trifluoro...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243360(5-{5-[3-(4- Trifluoromethyl- pyrimidin-2-ylamino)-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243359(4-{5-[3-(4-Thiophen-2- yl-pyrimidin-2-ylamino)- ph...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243357(4-{5-[3-(4-Isopropyl- pyrimidin-2-ylamino)- phenyl...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243345(4-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243355(5-{5-[3-(4-Isopropyl- pyrimidin-2-ylamino)- phenyl...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243354(4-{5-[3-(4-Phenyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243353(6-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243352(4-{5-[3-(4- Trifluoromethyl- pyrimidin-2-ylamino)-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243351(4-{5-[3-(4-Ethyl- pyrimidin-2-ylamino)- phenyl]-ox...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243350(4-{5-[3-(4-Methyl- pyrimidin-2-ylamino)-5- morphol...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243349(4-{5-[3-Methy1-5-(4- trifluoromethyl-pyrimidin- 2-...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243348(4-{5-[2-(2-Morpholin-4- yl-ethoxy)-5-(4-thiophen- ...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243347(4-{5-[3-Morpholin-4- ylmethy1-5-(4- trifluoromethy...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243346(2-{3-[2-(8-Oxo-4,7- diaza-spiro[2.5]oct-4-yl)- oxa...)
Affinity DataIC50: 500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243365(4-{5-[3-(4-Methyl- pyridin-2-ylamino)- phenyl]oxaz...)
Affinity DataIC50: 1.25E+3nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243358(4-{5-[3-(4-Morpholin-4- yl-pyrimidin-2-ylamino)- p...)
Affinity DataIC50: 2.00E+3nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetTyrosine-protein kinase SYK(Human)
Ab Science

US Patent
LigandPNGBDBM243364(4-{5-[2-Methyl-3-(4- methyl-pyrimidin-2- ylamino)-...)
Affinity DataIC50: 2.00E+3nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
In DepthDetails
US Patent