Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 231
TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, FC 4.037 (N- CDX) | US10053433, Casode...)
Affinity DataIC50: 15nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, FC 4.037 (N- CDX) | US10053433, Casode...)
Affinity DataIC50: 190nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, FC 4.037 (N- CDX) | US10053433, Casode...)
Affinity DataIC50: 360nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239191(US10053433, FC 3.077)
Affinity DataIC50: 490nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM242618(US10053433, FC 4.025)
Affinity DataIC50: 580nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM242588(US10053433, FC 4.039)
Affinity DataIC50: 750nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, FC 4.037 (N- CDX) | US10053433, Casode...)
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM242618(US10053433, FC 4.025)
Affinity DataIC50: 1.29E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239363(US10053433, FC 4.126)
Affinity DataIC50: 1.55E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 1.94E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239316(US10053433, FC 4.116)
Affinity DataIC50: 2.53E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50094975(US10053433, ARN-509 | ARN-509 | JNJ-56021927 | apa...)
Affinity DataIC50: 3.11E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50094975(US10053433, ARN-509 | ARN-509 | JNJ-56021927 | apa...)
Affinity DataIC50: 3.28E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM242578(US10053433, FC 4.127)
Affinity DataIC50: 7.26E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 8.61E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM242578(US10053433, FC 4.127)
Affinity DataIC50: 8.74E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239363(US10053433, FC 4.126)
Affinity DataIC50: 1.24E+4nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50094975(US10053433, ARN-509 | ARN-509 | JNJ-56021927 | apa...)
Affinity DataIC50: 1.95E+4nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239507(US10053433, FC 4.125)
Affinity DataIC50: 2.24E+4nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAndrogen receptor(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM239316(US10053433, FC 4.116)
Affinity DataIC50: 7.17E+4nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
In DepthDetails
US Patent